The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension
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DOI: 10.1161/hypertensionaha.122.19397
Abstract: Background: Autophagy plays an important role in the pathogenesis of pulmonary hypertension (PH). ROC-325 is a novel small molecule lysosomal autophagy inhibitor that has more potent anticancer activity than the antimalarial drug hydroxychloroquine, the latter… read more here.
Keywords: roc 325; pulmonary hypertension; lysosomal autophagy; nitric oxide ... See more keywords