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NMMHC IIA Inhibition Ameliorates Cerebral Ischemic/Reperfusion-Induced Neuronal Apoptosis Through Caspase-3/ROCK1/MLC Pathway

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Published in 2020 at "Drug Design, Development and Therapy"

DOI: 10.2147/dddt.s230882

Abstract: Purpose Our previous studies have indicated that non-muscle myosin heavy chain IIA (NMMHC IIA) is involved in H2O2-induced neuronal apoptosis, which is associated with the positive feedback loop of caspase-3/ROCK1/MLC pathway. However, the neuroprotective effect… read more here.

Keywords: iia; rock1 mlc; neuronal apoptosis; nmmhc iia ... See more keywords