Conditional deficiency of Rho‐associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice
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DOI: 10.1002/2211-5463.13802
Abstract: The Ras homology (Rho) family of GTPases serves various functions, including promotion of cell migration, adhesion, and transcription, through activation of effector molecule targets. One such pair of effectors, the Rho‐associated coiled‐coil kinases (ROCK1 and… read more here.
Keywords: rock1 rock2; mice; cell; adult mice ... See more keywords
The level of ROCK1 and ROCK2 in patients with pulmonary hypertension in plateau area
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DOI: 10.1038/s41598-018-27321-4
Abstract: Pulmonary hypertension (PH) is defined as the mean pulmonary artery pressure (mPAP) ≥25 mmHg under the sea level in resting state. ROCK1 and ROCK2 can be combined to cause the damage of vascular endothelial function. To… read more here.
Keywords: rock1 rock2; plateau; pulmonary hypertension; level ... See more keywords