ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes.
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DOI: 10.1073/pnas.2209184120
Abstract: Monocytes play a key role in innate immunity by eliminating pathogens, releasing high levels of cytokines, and differentiating into several cell types, including macrophages and dendritic cells. Similar to other phagocytes, monocytes produce superoxide anions… read more here.
Keywords: oxidase activation; human monocytes; nadph oxidase; rock2 interacts ... See more keywords