The SLCO1A2 -189_-188InsA polymorphism reduces clearance of rocuronium in patients submitted to elective surgeries
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DOI: 10.1007/s00228-017-2243-1
Abstract: PurposeRocuronium (ROC) is a neuromuscular blocker mainly eliminated by biliary excretion dependent on organic anion transporting polypeptide 1A2 (OATP1A2) hepatocellular uptake. However, the influence of SLCO1A2 (gene encoding OATP1A2) genetic polymorphism on ROC pharmacokinetics was… read more here.
Keywords: rocuronium; 189 188insa; slco1a2 189; clearance ... See more keywords
The Pringle maneuver reduces the infusion rate of rocuronium required to maintain surgical muscle relaxation during hepatectomy
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DOI: 10.1007/s00540-018-2498-4
Abstract: IntroductionWe investigated the continuous infusion rates of rocuronium necessary to obtain the surgical muscle relaxation before, during, and after the Pringle maneuver on patients who underwent hepatectomy.MethodsFifteen patients were induced by total intravenous anesthesia with… read more here.
Keywords: pringle maneuver; rocuronium; infusion; muscle ... See more keywords
Effects of cardiac output on the onset of rocuronium-induced neuromuscular block in elderly patients
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DOI: 10.1007/s00540-018-2510-z
Abstract: PurposeThe aim of this study was to elucidate the relationship between the onset of rocuronium-induced neuromuscular block and arterial pressure-based cardiac output (CO) in elderly patients.MethodsForty elderly patients aged 65–83 years were enrolled in this study.… read more here.
Keywords: rocuronium; rocuronium induced; induced neuromuscular; elderly patients ... See more keywords
Rocuronium Bromide Intravenous Solution Maruishi® is more suitable than ESLAX Intravenous® during rapid-sequence induction of anesthesia
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DOI: 10.1007/s00540-019-02673-x
Abstract: Rocuronium Bromide Intravenous Solution® (Maruishi Pharmaceutical Co., Ltd, Osaka, Japan) is a newly developed generic drug and we have noticed that compared with conventional rocuronium formulations [e.g. Esmeron (Eslax), MSD Co. Ltd., Tokyo, Japan], rocuronium… read more here.
Keywords: rocuronium; maruishi; movement; rocuronium maruishi ... See more keywords
Appropriate dosing of sugammadex and rocuronium for reversal of neuromuscular blockade and reparalysis
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DOI: 10.1007/s00540-020-02842-3
Abstract: Sugammadex is extensively used since its introduction to our country in 2010; however, there is a paucity of data showing its optimal dose for reversal of neuromuscular blockade, particularly shortly after administration of muscle relaxants.… read more here.
Keywords: reversal neuromuscular; reversal; rocuronium; sugammadex ... See more keywords
Emergency Department Intubation Success With Succinylcholine Versus Rocuronium: A National Emergency Airway Registry Study
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DOI: 10.1016/j.annemergmed.2018.03.042
Abstract: Study objective: Although both succinylcholine and rocuronium are used to facilitate emergency department (ED) rapid sequence intubation, the difference in intubation success rate between them is unknown. We compare first‐pass intubation success between ED rapid… read more here.
Keywords: rocuronium; intubation; succinylcholine versus; intubation success ... See more keywords
Recovery from rocuronium with sugammadex in children premedicated with dexamethasone for prevention of postoperative nausea and vomiting
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DOI: 10.1016/j.egja.2016.11.005
Abstract: Abstract Sugammadex is a cyclodextrin specifically designed to reverse the action of rocuronium through encapsulation. Theoretically, it is possible that sugammadex can encapsulate cortisone. The primary outcome of the present study is to investigate any… read more here.
Keywords: rocuronium; group; sugammadex; group met ... See more keywords
Recovery from rocuronium-induced neuromuscular block was longer in the larynx than in the pelvic limb of anesthetized dogs.
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DOI: 10.1016/j.vaa.2016.04.001
Abstract: OBJECTIVE To determine if neuromuscular monitoring at the pelvic limb accurately reflects neuromuscular function in the larynx after administration of rocuronium in anesthetized dogs. STUDY DESIGN Prospective experimental study. ANIMALS Six healthy Beagle dogs. METHODS… read more here.
Keywords: rocuronium; limb; anesthetized dogs; pelvic limb ... See more keywords
949: PARALYTIC TACHYPHYLAXIS AND ECMO
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DOI: 10.1097/01.ccm.0000810120.07587.36
Abstract: INTRODUCTION: Critically ill adult patients requiring extracorporeal membrane oxygenation (ECMO) with prolonged paralytic exposure may develop potential tachyphylaxis. This phenomenon has yet to be described within the ECMO literature. DESCRIPTION: A 49-year-old male (70 kg)… read more here.
Keywords: rocuronium; tachyphylaxis ecmo; tachyphylaxis; mcg min ... See more keywords
Effects of magnesium chloride on rocuronium-induced neuromuscular blockade and sugammadex reversal in an isolated rat phrenic nerve–hemidiaphragm preparation: An in-vitro study
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DOI: 10.1097/eja.0000000000000714
Abstract: BACKGROUND Magnesium potentiates the effects of nondepolarising muscle relaxants. However, few studies have used magnesium chloride (MgCl2). Sugammadex reverses neuromuscular block by steroidal nondepolarising muscle relaxants. OBJECTIVES To assess the effects of MgCl2 on rocuronium-induced… read more here.
Keywords: rocuronium; group; study; sugammadex ... See more keywords
Comparison of rocuronium requirement in children with continuous infusion versus intermittent bolus: A randomised controlled trial
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DOI: 10.1097/eja.0000000000000934
Abstract: BACKGROUND Minimising rocuronium administration during paediatric surgery helps to reduce the incidence of residual muscular blockade. OBJECTIVE To determine whether intermittent bolus injection (Bolus group) or continuous infusion (group) requires the lesser amount of rocuronium.… read more here.
Keywords: rocuronium; bolus; infusion group; continuous infusion ... See more keywords