E3 ubiquitin ligase RNF123-deficient mice exhibit reduced parasitemia and mortality in rodent malaria (Plasmodium yoelii 17XL) infection.
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DOI: 10.1016/j.parint.2022.102542
Abstract: Increased levels of several human ubiquitin ligases, including ring finger protein 123 (RNF123), in red blood cells with Plasmodium falciparum infection, have been reported. RNF123 is an E3 ubiquitin ligase that is highly expressed in… read more here.
Keywords: infection; rnf123 deficient; rodent malaria; deficient mice ... See more keywords
Plasmodium vinckei genomes provide insights into the pan-genome and evolution of rodent malaria parasites
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DOI: 10.1186/s12915-021-00995-5
Abstract: Background Rodent malaria parasites (RMPs) serve as tractable tools to study malaria parasite biology and host-parasite-vector interactions. Among the four RMPs originally collected from wild thicket rats in sub-Saharan Central Africa and adapted to laboratory… read more here.
Keywords: plasmodium vinckei; rodent malaria; malaria parasites; biology ... See more keywords
Genetic mapping of determinants in drug resistance, virulence, disease susceptibility, and interaction of host-rodent malaria parasites.
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DOI: 10.2139/ssrn.4070356
Abstract: Genetic mapping has been widely employed to search for genes linked to phenotypes/traits of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice, many genetic crosses of rodent malaria parasites have… read more here.
Keywords: host; malaria parasites; rodent malaria; genetic mapping ... See more keywords