Bridging the gap between rodents and humans: The role of non‐human primates in oxytocin research
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Primatology"
DOI: 10.1002/ajp.22756
Abstract: Oxytocin (OT), a neuropeptide that acts in the brain as a neuromodulator, has been long known to shape maternal physiology and behavior in mammals, however its role in regulating social cognition and behavior in primates… read more here.
Keywords: gap; non human; social cognition; rodents humans ... See more keywords
Insulin‐like peptide 3 in domestic animals with normal and abnormal reproductive functions, in comparison to rodents and humans
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12485
Abstract: Insulin‐like peptide 3 (INSL3) is a circulating hormone secreted from only testis and ovaries in mammals. Findings on INSL3 have been gathered from subjects with normal and abnormal reproductive statuses, especially rodents and humans. However,… read more here.
Keywords: rodents humans; insulin like; like peptide; domestic animals ... See more keywords
Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.09.065
Abstract: A hallmark of aging is a decline in metabolic homeostasis, which is attenuated by dietary restriction (DR). However, the interaction of aging and DR with the metabolome is not well understood. We report that DR… read more here.
Keywords: modulated aging; sarcosine uniquely; rodents humans; dietary restriction ... See more keywords
Prefrontal Cortex Development in Health and Disease: Lessons from Rodents and Humans
Sign Up to like & getrecommendations! Published in 2021 at "Trends in Neurosciences"
DOI: 10.1016/j.tins.2020.10.017
Abstract: The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive and social abilities that reach their maximum expression in… read more here.
Keywords: rodents humans; cortex development; development health; development ... See more keywords
Malaria-induced Alterations of Drug Kinetics and Metabolism in Rodents and Humans.
Sign Up to like & getrecommendations! Published in 2021 at "Current drug metabolism"
DOI: 10.2174/1389200221999210101232057
Abstract: BACKGROUND Infections and inflammation lead to a downregulation of drug metabolism and kinetics in experimental animals. These changes in the expression and activities of drug-metabolizing enzymes may affect the effectiveness and safety of pharmacotherapy of… read more here.
Keywords: metabolism; malaria induced; drug; rodents humans ... See more keywords
Exercise-Induced Adaptations to Adipose Tissue Thermogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00270
Abstract: Exercise training results in beneficial adaptations to numerous tissues and offers protection against metabolic disorders including obesity and type 2 diabetes. Multiple studies have indicated that both white (WAT) and brown (BAT) adipose tissue may… read more here.
Keywords: exercise induced; induced adaptations; rodents humans; adipose tissue ... See more keywords
Effects of Palmitoylethanolamide on Neurodegenerative Diseases: A Review from Rodents to Humans
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12050667
Abstract: Palmitoylethanolamide (PEA) stands out among endogenous lipid mediators for its neuroprotective, anti-inflammatory, and analgesic functions. PEA belonging to the N-acetylanolamine class of phospholipids was first isolated from soy lecithin, egg yolk, and peanut flour. It… read more here.
Keywords: rodents humans; review rodents; effects palmitoylethanolamide; palmitoylethanolamide neurodegenerative ... See more keywords