Autoantibodies against “rods and rings”-related IMPDH2 in hepatitis C genotype 1 and DAA therapy in a “real life” cohort
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DOI: 10.1007/s00430-017-0516-z
Abstract: Autoantibodies against inosine-5′-monophosphate-dehydrogenase-2 (IMPDH2; “rods and rings” pattern) develop in chronic hepatitis C (CHC) patients under treatment with peg-interferon (IFN) and ribavirin (RBV), an inhibitor of IMPDH2. We investigated the influence of the alternative therapy… read more here.
Keywords: daa; rods rings; anti impdh2; therapy ... See more keywords
Autoantibodies to cytoplasmic rods and rings in patients with hepatitis C virus infection treated with direct-acting antivirals: The role of prior treatment with interferon plus ribavirin.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterologia y hepatologia"
DOI: 10.1016/j.gastrohep.2018.08.005
Abstract: INTRODUCTION The cytoplasmic rods-rings (RR) pattern is found in hepatitis C (HCV) patients treated with interferon-ribavirin when studied with ANA-IIF. Ribavirin aggregates/induces antigenic changes in IMPDH-2, an enzyme necessary for ribavirin action. PATIENTS AND METHOD… read more here.
Keywords: rbv; treated direct; hcv; rods rings ... See more keywords
The value of anti‐rods and rings antibodies in Western China population: A retrospective study
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DOI: 10.1111/sji.12848
Abstract: The study aimed to retrospectively investigate the clinical significance of anti‐rods and rings (anti‐RR) antibodies in antinuclear antibodies (ANAs) test samples of western China. Between January 2016 and November 2018, the laboratory data and clinical… read more here.
Keywords: anti rods; study; value anti; rods rings ... See more keywords
The value of anti‐rods and rings antibodies in Chinese population of Dalian City: A retrospective study
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DOI: 10.1111/sji.13254
Abstract: The study aimed to investigate the clinical significance of anti‐rods and rings (anti‐RR) antibodies in antinuclear antibodies (ANAs) test samples retrospectively. The laboratory data and clinical details of patients with positive anti‐RR antibodies were collected… read more here.
Keywords: anti rods; rods rings; value anti; rings antibodies ... See more keywords