Identification of runs of homozygosity in Western honey bees (Apis mellifera) using whole‐genome sequencing data
Sign Up to like & getrecommendations! Published in 2023 at "Ecology and Evolution"
DOI: 10.1002/ece3.9723
Abstract: Abstract Runs of homozygosity (ROH) are continuous homozygous segments that arise through the transmission of haplotypes that are identical by descent. The length and distribution of ROH segments provide insights into the genetic diversity of… read more here.
Keywords: apis mellifera; honey bees; roh; whole genome ... See more keywords
Evaluating the performance of a predictive modeling approach to identifying members at high-risk of hospitalization
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Economics"
DOI: 10.1080/13696998.2019.1666854
Abstract: Abstract Aims: To evaluate the risk-of-hospitalization (ROH) models developed at Blue Cross Blue Shield of Louisiana (BCBSLA) and compare this approach to the DxCG risk-score algorithms utilized by many health plans. Materials and Methods: Time… read more here.
Keywords: roh; cross; blue cross; risk hospitalization ... See more keywords
Runs of homozygosity: current knowledge and applications in livestock.
Sign Up to like & getrecommendations! Published in 2017 at "Animal genetics"
DOI: 10.1111/age.12526
Abstract: This review presents a broader approach to the implementation and study of runs of homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH and their practical implications. ROH are continuous homozygous segments that… read more here.
Keywords: information; homozygosity; runs homozygosity; homozygosity current ... See more keywords
Runs of homozygosity reveal genome‐wide autozygosity in Italian sheep breeds
Sign Up to like & getrecommendations! Published in 2018 at "Animal Genetics"
DOI: 10.1111/age.12634
Abstract: The availability of dense single nucleotide polymorphism (SNP) assays allows for the determination of autozygous segments based on runs of consecutive homozygous genotypes (ROH). The aim of the present study was to investigate the occurrence… read more here.
Keywords: valle del; italian sheep; roh; sheep breeds ... See more keywords
Runs of homozygosity reveal past bottlenecks and contemporary inbreeding across diverging populations of an island‐colonizing bird
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Ecology"
DOI: 10.1111/mec.16865
Abstract: Genomes retain evidence of the demographic history and evolutionary forces that have shaped populations and drive speciation. Across island systems, contemporary patterns of genetic diversity reflect population demography, including colonization events, bottlenecks, gene flow and… read more here.
Keywords: diverging populations; roh; diversity; across diverging ... See more keywords
Assessing runs of Homozygosity: a comparison of SNP Array and whole genome sequence low coverage data
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-4489-0
Abstract: BackgroundRuns of Homozygosity (ROH) are genomic regions where identical haplotypes are inherited from each parent. Since their first detection due to technological advances in the late 1990s, ROHs have been shedding light on human population… read more here.
Keywords: snp array; roh; low coverage; homozygosity ... See more keywords
The distribution of runs of homozygosity and selection signatures in six commercial meat sheep breeds
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DOI: 10.1371/journal.pone.0176780
Abstract: Domestication and the subsequent selection of animals for either economic or morphological features can leave a variety of imprints on the genome of a population. Genomic regions subjected to high selective pressures often show reduced… read more here.
Keywords: breed; runs homozygosity; selection; roh ... See more keywords
Genomic inbreeding and runs of homozygosity analysis of indigenous cattle populations in southern China
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271718
Abstract: Runs of homozygosity (ROH) are continuous homozygous segments from the common ancestor of parents. Evaluating ROH pattern can help to understand inbreeding level and genetic basis of important traits. In this study, three representative cattle… read more here.
Keywords: genes related; roh; cattle populations; homozygosity ... See more keywords
Runs of homocigosity and its association with productive traits in Mexican Holstein cattle
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0274743
Abstract: The objective of this study was to describe the runs of homozygosity (ROH) detected in the Mexican Holstein population and to associate them with milk, fat and protein yields, and conformation final score. After imputation… read more here.
Keywords: roh; homocigosity association; runs homocigosity; mexican holstein ... See more keywords
Increased runs of homozygosity in the autosomal genome of Brazilian individuals with neurodevelopmental delay/intellectual disability and/or multiple congenital anomalies investigated by chromosomal microarray analysis
Sign Up to like & getrecommendations! Published in 2022 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2020-0480
Abstract: Abstract Runs of homozygosity (ROH) in the human genome may be clinically relevant. The aim of this study was to report the frequency of increased ROH of the autosomal genome in individuals with neurodevelopmental delay/intellectual… read more here.
Keywords: autosomal genome; roh; homozygosity; genome ... See more keywords
A heuristic method to identify runs of homozygosity associated with reduced performance in livestock.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of animal science"
DOI: 10.2527/jas2017.1664
Abstract: Although, for the most part, genome-wide metrics are currently used in managing livestock inbreeding, genomic data offer, in principle, the ability to identify functional inbreeding. Here, we present a heuristic method to identify haplotypes contained… read more here.
Keywords: reduced performance; heuristic method; performance; roh ... See more keywords