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   Articles with "role" as a keyword



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Association of Perceived Role Misidentification With Use of Role Identity Badges Among Resident Physicians

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.24236

Abstract: This quality improvement study assesses the implications of providing medical trainees with a wearable badge that indicates their physician role on the patient care team. read more here.

Keywords: role; use role; association perceived; role misidentification ... See more keywords
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The Role of Environmental Factors in the Pathogenesis of Inflammatory Bowel Diseases: A Review

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recommendations! Published in 2017 at "JAMA Pediatrics"

DOI: 10.1001/jamapediatrics.2017.2571

Abstract: Importance Inflammatory bowel diseases (IBD), such as Crohn disease and ulcerative colitis, are chronic relapsing conditions that affect a growing number of children worldwide. The pathogenesis of these disorders is complex and thought to be… read more here.

Keywords: risk; environmental factors; inflammatory bowel; bowel diseases ... See more keywords
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The role of OleA His285 in orchestration of long‐chain acyl‐coenzyme A substrates

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recommendations! Published in 2018 at "FEBS Letters"

DOI: 10.1002/1873-3468.13004

Abstract: Renewable production of hydrocarbons is being pursued as a petroleum‐independent source of commodity chemicals and replacement for biofuels. The bacterial biosynthesis of long‐chain olefins represents one such platform. The process is initiated by OleA catalyzing… read more here.

Keywords: olea; acyl coenzyme; long chain; role ... See more keywords
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The key role of ergothioneine in label‐free surface‐enhanced Raman scattering spectra of biofluids: a retrospective re‐assessment of the literature

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14312

Abstract: Label‐free surface‐enhanced Raman scattering (SERS) has recently gained attention in the field of liquid biopsy as a rapid and relatively inexpensive technique that could significantly ease clinical diagnosis and prognosis by investigating a biofluid sample… read more here.

Keywords: label free; role; surface enhanced; ergothioneine ... See more keywords
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Role of L1CAM in retinoblastoma tumorigenesis: identification of novel therapeutic targets.

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recommendations! Published in 2021 at "Molecular oncology"

DOI: 10.1002/1878-0261.13054

Abstract: The study presented focuses on the role of the neuronal cell adhesion molecule L1CAM in retinoblastoma (RB), the most common malignant intraocular childhood tumor. L1CAM is differentially expressed in a variety of human cancers and… read more here.

Keywords: cell lines; l1cam; role; l1cam retinoblastoma ... See more keywords
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Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1/RIPK1 signaling.

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recommendations! Published in 2023 at "Molecular oncology"

DOI: 10.1002/1878-0261.13374

Abstract: Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity-dependent labeling (PDL) with biotin followed… read more here.

Keywords: abi1; role; ripk1; regulation ... See more keywords
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Analysis of the role of mutations in the KMT2D histone lysine methyltransferase in bladder cancer

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recommendations! Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12600

Abstract: Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators; dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis. Here, we performed an integrated analysis of 50 HMTs in bladder cancer and… read more here.

Keywords: bladder cancer; histone lysine; analysis; bladder ... See more keywords
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MiR‐17‐3p inhibits osteoblast differentiation by downregulating Sox6 expression

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recommendations! Published in 2020 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12979

Abstract: Osteoporosis and osteoarthritis are orthopedic disorders that affect millions of elderly people worldwide; stimulation of bone formation is a potential therapeutic strategy for the treatment of these conditions. As the only bone‐forming cells, osteoblasts play… read more here.

Keywords: mir; differentiation; role; osteoblast differentiation ... See more keywords
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The role of RNA regulators, quorum sensing and c-di-GMP in bacterial biofilm formation.

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recommendations! Published in 2022 at "FEBS open bio"

DOI: 10.1002/2211-5463.13389

Abstract: Biofilms provide an ecological advantage against many environmental stressors, such as pH and temperature, making it the most common life‐cycle stage for many bacteria. These protective characteristics make eradication of bacterial biofilms challenging. This is… read more here.

Keywords: role; biofilm formation; biofilm; gmp ... See more keywords
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A 3D Osteosarcoma Model with Bone‐Mimicking Cues Reveals a Critical Role of Bone Mineral and Informs Drug Discovery

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202200768

Abstract: Osteosarcoma (OS) is an aggressive bone cancer for which survival has not improved over three decades. While biomaterials have been widely used to engineer 3D soft‐tissue tumor models, the potential of engineering 3D biomaterials‐based OS… read more here.

Keywords: drug discovery; role; bone; model ... See more keywords
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Stressing the Role of DNA as a Drug Carrier: Synthesis of DNA-Drug Conjugates through Grafting Chemotherapeutics onto Phosphorothioate Oligonucleotides.

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recommendations! Published in 2019 at "Advanced materials"

DOI: 10.1002/adma.201807533

Abstract: To stress the role of deoxyribonucleic acid (DNA) as a drug carrier, an efficient conjugation strategy in which chemotherapeutics can be grafted onto a phosphorothiolated DNA backbone through the reaction between the phosphorothioate group (PS)… read more here.

Keywords: drug carrier; dna; ptx; drug ... See more keywords