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   Articles with "role" as a keyword



Association of Perceived Role Misidentification With Use of Role Identity Badges Among Resident Physicians

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.24236

Abstract: This quality improvement study assesses the implications of providing medical trainees with a wearable badge that indicates their physician role on the patient care team. read more here.

Keywords: role; use role; association perceived; role misidentification ... See more keywords
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The Role of Environmental Factors in the Pathogenesis of Inflammatory Bowel Diseases: A Review

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recommendations! Published in 2017 at "JAMA Pediatrics"

DOI: 10.1001/jamapediatrics.2017.2571

Abstract: Importance Inflammatory bowel diseases (IBD), such as Crohn disease and ulcerative colitis, are chronic relapsing conditions that affect a growing number of children worldwide. The pathogenesis of these disorders is complex and thought to be… read more here.

Keywords: risk; environmental factors; inflammatory bowel; bowel diseases ... See more keywords

The role of OleA His285 in orchestration of long‐chain acyl‐coenzyme A substrates

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recommendations! Published in 2018 at "FEBS Letters"

DOI: 10.1002/1873-3468.13004

Abstract: Renewable production of hydrocarbons is being pursued as a petroleum‐independent source of commodity chemicals and replacement for biofuels. The bacterial biosynthesis of long‐chain olefins represents one such platform. The process is initiated by OleA catalyzing… read more here.

Keywords: olea; acyl coenzyme; long chain; role ... See more keywords

The key role of ergothioneine in label‐free surface‐enhanced Raman scattering spectra of biofluids: a retrospective re‐assessment of the literature

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14312

Abstract: Label‐free surface‐enhanced Raman scattering (SERS) has recently gained attention in the field of liquid biopsy as a rapid and relatively inexpensive technique that could significantly ease clinical diagnosis and prognosis by investigating a biofluid sample… read more here.

Keywords: label free; role; surface enhanced; ergothioneine ... See more keywords

YAP1 modulation of primary cilia‐mediated ciliogenesis in 2D and 3D prostate cancer models

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recommendations! Published in 2024 at "FEBS Letters"

DOI: 10.1002/1873-3468.15029

Abstract: The primary cilium, a non‐motile organelle present in most human cells, plays a crucial role in detecting microenvironmental changes and regulating intracellular signaling. Its dysfunction is linked to various diseases, including cancer. We explored the… read more here.

Keywords: cancer; role; yap1 modulation; primary cilium ... See more keywords

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

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recommendations! Published in 2025 at "Febs Letters"

DOI: 10.1002/1873-3468.70006

Abstract: Leucine zipper EF‐hand containing transmembrane protein‐1 (LETM1) plays a critical role in mitochondrial function, with haploinsufficiency linked to Wolf‐Hirschhorn syndrome. Here, we present the solution NMR structure of the calcium (Ca2+)‐depleted LETM1 EF‐hand domain, revealing… read more here.

Keywords: closed conformation; hand; role; letm1 hand ... See more keywords

The multifunctional role of the protease HtrA in Helicobacter pylori pathogenesis.

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recommendations! Published in 2025 at "FEBS letters"

DOI: 10.1002/1873-3468.70226

Abstract: The HtrA family of proteins is known for its dual role as chaperones and proteases. In Helicobacter pylori (H. pylori), HtrA's chaperone and proteolytic activities are crucial for the bacterium's survival and successful host infection.… read more here.

Keywords: role; multifunctional role; role protease; helicobacter pylori ... See more keywords
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Role of L1CAM in retinoblastoma tumorigenesis: identification of novel therapeutic targets.

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recommendations! Published in 2021 at "Molecular oncology"

DOI: 10.1002/1878-0261.13054

Abstract: The study presented focuses on the role of the neuronal cell adhesion molecule L1CAM in retinoblastoma (RB), the most common malignant intraocular childhood tumor. L1CAM is differentially expressed in a variety of human cancers and… read more here.

Keywords: cell lines; l1cam; role; l1cam retinoblastoma ... See more keywords

Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1/RIPK1 signaling.

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recommendations! Published in 2023 at "Molecular oncology"

DOI: 10.1002/1878-0261.13374

Abstract: Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity-dependent labeling (PDL) with biotin followed… read more here.

Keywords: abi1; role; ripk1; regulation ... See more keywords

Analysis of the role of mutations in the KMT2D histone lysine methyltransferase in bladder cancer

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recommendations! Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12600

Abstract: Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators; dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis. Here, we performed an integrated analysis of 50 HMTs in bladder cancer and… read more here.

Keywords: bladder cancer; histone lysine; analysis; bladder ... See more keywords
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MiR‐17‐3p inhibits osteoblast differentiation by downregulating Sox6 expression

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recommendations! Published in 2020 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12979

Abstract: Osteoporosis and osteoarthritis are orthopedic disorders that affect millions of elderly people worldwide; stimulation of bone formation is a potential therapeutic strategy for the treatment of these conditions. As the only bone‐forming cells, osteoblasts play… read more here.

Keywords: mir; differentiation; role; osteoblast differentiation ... See more keywords