Role of Ageing and Oxidative Stress in Regulation of Amyloid-Degrading Enzymes and Development of Neurodegeneration.
Sign Up to like & getrecommendations! Published in 2017 at "Current aging science"
DOI: 10.2174/1874609809666161111101111
Abstract: The accumulation of cerebral amyloid βpeptide (Aβ) is a key precipitating factor for neuronal cell death in Alzheimer's Disease (AD). However, brain Aβ levels are modifiable since there is a balance between its formation from… read more here.
Keywords: role ageing; ageing oxidative; degrading enzymes; amyloid degrading ... See more keywords
The Role of Ageing and Parenchymal Senescence on Macrophage Function and Fibrosis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.700790
Abstract: In this review, we examine senescent cells and the overlap between the direct biological impact of senescence and the indirect impact senescence has via its effects on other cell types, particularly the macrophage. The canonical… read more here.
Keywords: role ageing; ageing parenchymal; senescence; parenchymal senescence ... See more keywords