Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001256
Abstract: Abstract: Sunitinib is associated with cardiotoxicity through inhibition of AMP-protein kinase (AMPK) signaling. By contrast, the common antidiabetic agent metformin has demonstrated cardioprotection through indirect AMPK activation. In this study, we investigate the effects of… read more here.
Keywords: sunitinib induced; sunitinib; cardiotoxicity; role ampk ... See more keywords
Role of AMPK in autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.1015500
Abstract: Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved catabolic process that involves an intracellular degradation system in which cytoplasmic components, such… read more here.
Keywords: role ampk; ampk autophagy; ampk; process ... See more keywords