Abstract LB044: Modeling the role of ARID1A in colon cancer using patient-derived organoids
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb044
Abstract: Loss-of-function (LOF) mutations in genes encoding subunits of SWI/SNF chromatin remodeling complexes are found in approximately 25% of human cancers. Colorectal cancers (CRC), the second leading cause of cancer related deaths, are particularly vulnerable to… read more here.
Keywords: role arid1a; arid1a colon; arid1a; cancer ... See more keywords
The somatic mutational landscape and role of the ARID1A gene in hepatocellular carcinoma
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DOI: 10.2139/ssrn.4095314
Abstract: Introduction Hepatocellular carcinoma (HCC) is one of the most common malignant tumours worldwide. Clarification of the somatic mutational landscape of important genes could reveal new therapeutic targets and facilitate individualized therapeutic approaches for HCC patients.… read more here.
Keywords: role arid1a; hepatocellular carcinoma; somatic mutational; hcc ... See more keywords
The Role of ARID1A in Endometrial Cancer and the Molecular Pathways Associated With Pathogenesis and Cancer Progression
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DOI: 10.21873/invivo.11524
Abstract: AT-rich interaction domain 1A gene (ARID1A) encodes for a subunit of the switch/sucrose non-fermentable (SWI/SNF) complex, a chromatin remodeling complex, and it has been implicated in the pathogenesis of various cancer types. In this review,… read more here.
Keywords: role arid1a; pathogenesis; endometrial cancer; cancer ... See more keywords