Articles with "role atropisomerism" as a keyword



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Unraveling the Pivotal Role of Atropisomerism for Cellular Internalization

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Published in 2022 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.2c05844

Abstract: The intrinsic challenge of large molecules to cross the cell membrane and reach intracellular targets is a major obstacle for the development of new medicines. We report how rotation along a single C–C bond, between… read more here.

Keywords: internalization; atropisomerism cellular; pivotal role; role atropisomerism ... See more keywords