Rest and Digest—The Basal Role of Autophagy in Neurons and Its Relevance to Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.29165
Abstract: in the basal role of autophagy in and its regulation of mitochondrial-derived in fl ammation as part of con-trol. In Brain-derived autophagosome pro fi ling the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in… read more here.
Keywords: autophagy neurons; role; basal role; rest digest ... See more keywords
Role of autophagy in triacylglycerol biosynthesis in Chlamydomonas reinhardtii revealed by chemical inducer and inhibitors
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-017-1166-7
Abstract: Autophagy mediates degradation and recycling of cellular components and plays an important role in senescence and adaptive responses to biotic and abiotic stresses. Nutrient deprivation has been shown to trigger triacylglycerol (TAG) accumulation and also… read more here.
Keywords: accumulation; role; role autophagy; triacylglycerol ... See more keywords
New insights on the role of autophagy in the pathogenesis and treatment of melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular biology reports"
DOI: 10.1007/s11033-020-05886-6
Abstract: Despite the depth of knowledge concerning the pathogenesis of melanoma, the most aggressive type of skin cancer, the prognosis and survival of patients still remain a challenge. In addition, responses to chemotherapy and immunotherapy are… read more here.
Keywords: melanoma; treatment melanoma; role autophagy; pathogenesis ... See more keywords
The putative role of autophagy in the pathogenesis of abdominal aortic aneurysms.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.01.017
Abstract: Abdominal aortic aneurysms (AAA) are a significant cause of worldwide mortality and morbidity. While the histopathological characteristics of AAA are well documented, the cellular and molecular mechanisms involved in the pathogenesis of AAA are not… read more here.
Keywords: aortic aneurysms; pathogenesis; autophagy; abdominal aortic ... See more keywords
Role of autophagy in the periodontal ligament reconstruction during orthodontic tooth movement in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Dental Sciences"
DOI: 10.1016/j.jds.2020.02.005
Abstract: Background/purpose Autophagy, a lysosome-based degradation pathway that is reportedly activated by mechanical stress and nutrient deprivation, plays an important role in various physiological and pathological events. The present study investigated the level of autophagy and… read more here.
Keywords: tnf expression; tooth movement; role autophagy; orthodontic tooth ... See more keywords
Clearing or subverting the enemy: Role of autophagy in protozoan infections.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117453
Abstract: The protozoan parasites are evolutionarily divergent, unicellular eukaryotic pathogens representing one of the essential sources of parasitic diseases. These parasites significantly affect the economy and cause public health burdens globally. Protozoan parasites share many cellular… read more here.
Keywords: protozoan; enemy role; subverting enemy; autophagy ... See more keywords
Role of autophagy in the pathogenesis of rheumatoid arthritis: Latest evidence and therapeutic approaches.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117734
Abstract: Autophagy is considered as an important intracellular mechanism that degrades cytoplasmic components to furnish additional energy. It has cytoprotective effects through the degradation of intracellular pathogens, damaged organelles, and protein aggregates. On the other hand,… read more here.
Keywords: rheumatoid; pathogenesis; evidence; rheumatoid arthritis ... See more keywords
The role of autophagy in acute myeloid leukemia development
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DOI: 10.1080/14737140.2023.2161518
Abstract: ABSTRACT Introduction Autophagy is a highly conservative self-degradative process. It aims at elimination-impaired proteins and cellular organelles. Previous research confirmed the autophagy role in cancer pathogenesis. Areas covered This article discusses the role of autophagy… read more here.
Keywords: myeloid leukemia; role; development; acute myeloid ... See more keywords
Defensosomes: a new role for autophagy proteins in innate immune defense.
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2146894
Abstract: In recent years, the contribution of exosomes to immunity, inflammation and host-pathogen interaction have been appreciated. Exosomes are small secreted extracellular vesicles from endosomal origin that contain a myriad of cellular molecules (protein, nucleic acids),… read more here.
Keywords: new role; autophagy proteins; proteins innate; role autophagy ... See more keywords
The Role of Autophagy in Hypoxia-Induced Neuroinflammation.
Sign Up to like & getrecommendations! Published in 2021 at "DNA and cell biology"
DOI: 10.1089/dna.2020.6186
Abstract: Autophagy is a critical cytoprotective mechanism that takes a hand in innate or adaptive immune responses. Hypoxia is a common pathophysiological mechanism that can lead to systemic pathological reactions. In recent years, the impact of… read more here.
Keywords: autophagy hypoxia; neuroinflammatory response; role; autophagy ... See more keywords
The Role of Autophagy in Murine Cytomegalovirus Hepatitis.
Sign Up to like & getrecommendations! Published in 2021 at "Viral immunology"
DOI: 10.1089/vim.2020.0024
Abstract: Autophagy is involved in the pathogenesis of multiple pathogen infection. Previous studies have reported that human cytomegalovirus (CMV) activates autophagy in the early stage of infection and then inhibits autophagy. Little is known about the… read more here.
Keywords: hepatitis; infection; expression; role autophagy ... See more keywords