The role of α-cells in islet function and glucose homeostasis in health and type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.01.004
Abstract: Pancreatic α-cells are the major source of glucagon, a hormone that counteracts the hypoglycemic action of insulin and strongly contributes to the correction of acute hypoglycemia. The mechanisms by which glucose controls glucagon secretion are… read more here.
Keywords: glucose homeostasis; cells islet; islet function; glucagon ... See more keywords
Role of B cells and antibodies in multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2019 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2019.101416
Abstract: Multiple sclerosis (MS) is a chronically progressive auto-immune mediated inflammatory demyelinating disease of the central nervous system (CNS) which manifests as disturbances in sensorimotor function and cognitive impairment. Although believed to be a T-cell mediated… read more here.
Keywords: sclerosis; role cells; multiple sclerosis; cell ... See more keywords
The role of B cells in atherosclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-018-0106-9
Abstract: The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis is most prominent and accounts for the majority of deaths globally. Antibody-producing B… read more here.
Keywords: cells atherosclerosis; immune responses; role cells; role ... See more keywords
The role of γδ T cells in the interaction between commensal and pathogenic bacteria in the intestinal mucosa.
Sign Up to like & getrecommendations! Published in 2022 at "International reviews of immunology"
DOI: 10.1080/08830185.2022.2076846
Abstract: The intestinal mucosa is an important structure involved in resistance to pathogen infection. It is mainly composed of four barriers, which have different but interrelated functions. Pathogenic bacteria can damage these intestinal mucosal barriers. Here,… read more here.
Keywords: pathogenic bacteria; cells interaction; commensal bacteria; role cells ... See more keywords
The prognostic role of NK cells and their ligands in squamous cell carcinoma of the head and neck: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "Oncoimmunology"
DOI: 10.1080/2162402x.2020.1747345
Abstract: ABSTRACT Background : Despite the improvement in therapeutic interventions, 5-year survival rates in Head and Neck Squamous Cell Carcinoma (HNSCC) are limited. HNSCC is an immunogenic cancer type for which molecular stratification markers are lacking.… read more here.
Keywords: role; role cells; head neck; cell ... See more keywords
The role of γδ T cells in the immunopathogenesis of inflammatory diseases: From basic biology to therapeutic targeting.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiad046
Abstract: Gamma-delta T cells are lymphocytes with an innate-like phenotype that can distribute to different tissues to reside and participate in homeostatic functions such as pathogen defence, tissue modelling and response to stress. These cells originate… read more here.
Keywords: diseases basic; immunopathogenesis inflammatory; role cells; inflammatory diseases ... See more keywords
The role of B cells in the pathogenesis of systemic sclerosis: an update.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac578
Abstract: The pathogenesis of systemic sclerosis (SSc) is incompletely understood but several lines of evidence suggest that B cells are involved. Effector B (Beff) cells are hyperactivated and produce autoantibodies (autoAbs) and regulatory B cells (Bregs)… read more here.
Keywords: systemic sclerosis; cells pathogenesis; role cells; fibrosis ... See more keywords
Antiviral CD19+CD27+ Memory B Cells Are Associated with Protection from Recurrent Asymptomatic Ocular Herpesvirus Infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.02057-21
Abstract: Reactivation of herpes simplex virus 1 (HSV-1) from latently infected neurons of the trigeminal ganglia (TG) leads to blinding recurrent herpetic disease in symptomatic (SYMP) individuals. Although the role of T cells in herpes immunity… read more here.
Keywords: role cells; memory cells; memory; hsv specific ... See more keywords
The Role of NK Cells in Pig-to-Human Xenotransplantation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Immunology Research"
DOI: 10.1155/2017/4627384
Abstract: Recruitment of human NK cells to porcine tissues has been demonstrated in pig organs perfused ex vivo with human blood in the early 1990s. Subsequently, the molecular mechanisms leading to adhesion and cytotoxicity in human… read more here.
Keywords: cells pig; pig human; role cells; role ... See more keywords
The Role of T Cells in Ovarian Physiology and Infertility
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.713650
Abstract: Infertility affects one in six couples worldwide, with more than 48 million couples affected internationally. The prevalence of infertility is increasing which is thought to be attributed to delayed child-bearing due to socioeconomic factors. Since… read more here.
Keywords: ovarian physiology; cells ovarian; physiology; infertility ... See more keywords
The Role of T Cells in Herpes Stromal Keratitis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00512
Abstract: The blinding inflammatory lesion stromal keratitis (SK), which occurs in some patients in response to ocular herpes simplex virus (HSV) infection, represents mainly an immune cell mediated inflammatory response to the virus infection. The principal… read more here.
Keywords: herpes stromal; lesion; role cells; cells herpes ... See more keywords