A role for cholesterol in Ebola virus
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DOI: 10.1126/science.371.6531.794-f
Abstract: Structural Virology The 2013–2016 Ebola epidemic in West Africa caused terrible disease and more than 10,000 deaths. The only protein on the surface of this virus is the glycoprotein (GP), which comprises the GP1 and… read more here.
Keywords: cholesterol ebola; ebola virus; cholesterol; role cholesterol ... See more keywords
Role of Cholesterol and Lipid Rafts in Cancer Signaling: A Promising Therapeutic Opportunity?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.622908
Abstract: Cholesterol is a lipid molecule that plays an essential role in a number of biological processes, both physiological and pathological. It is an essential structural constituent of cell membranes, and it is fundamental for biosynthesis,… read more here.
Keywords: cholesterol; role cholesterol; cholesterol lipid; cancer ... See more keywords
The role of cholesterol in invasion and growth of malaria parasites
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.984049
Abstract: Malaria parasites are unicellular eukaryotic pathogens that develop through a complex lifecycle involving two hosts, an anopheline mosquito and a vertebrate host. Throughout this lifecycle, the parasite encounters widely differing conditions and survives in distinct… read more here.
Keywords: growth; cholesterol; malaria parasites; invasion ... See more keywords
The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in IBD
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1028953
Abstract: Inflammatory Bowel Disease (IBD) is characterized by a loss of intestinal barrier function caused by an aberrant interaction between the immune response and the gut microbiota. In IBD, imbalance in cholesterol homeostasis and mitochondrial bioenergetics… read more here.
Keywords: mitochondrial bioenergetics; cholesterol mitochondrial; cholesterol; inflammasome ibd ... See more keywords
The Role of Cholesterol in the Interaction of the Lipid Monolayer with the Endocrine Disruptor Bisphenol-A
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DOI: 10.3390/membranes12080729
Abstract: Among pollutants of emerging concern, endocrine disruptors (ED) have been shown to cause side effects in humans and animals. Bisphenol-A (BPA) is an ED by-product of the plastic industry and one of the chemicals with… read more here.
Keywords: chol; bpa; monolayer; cholesterol ... See more keywords
Current Understanding of the Role of Cholesterol in the Life Cycle of Alphaviruses
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DOI: 10.3390/v13010035
Abstract: Enveloped viruses rely on different lipid classes present in cell membranes to accomplish several steps of their life cycle in the host. Particularly for alphaviruses, a medically important group of arboviruses, which are part of… read more here.
Keywords: life cycle; role cholesterol; cholesterol;