Role of chromatin modulation in the establishment of protozoan parasite infection for developing targeted chemotherapeutics
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DOI: 10.1007/s13237-021-00356-1
Abstract: Four major human infecting protozoan parasites (Plasmodium, Toxoplasma, Leishmania, and Trypanosoma) impose a substantial threat to health and socio-economic status causing significant morbidity and mortality in tropics and subtropics each year. Lack of effective drugs,… read more here.
Keywords: chromatin; role chromatin; protozoan; modulation ... See more keywords
Determinants and role of chromatin organization in acute leukemia
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DOI: 10.1038/s41375-020-0981-z
Abstract: DNA is compacted into higher order structures that have major implications in gene regulation. These structures allow for long-range interactions of DNA elements, such as the association of promoters with their cognate enhancers. In recent… read more here.
Keywords: leukemia determinants; chromatin; acute leukemia; determinants role ... See more keywords
Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease
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DOI: 10.3390/genes13061002
Abstract: Chromatin organization is essential to maintain a correct regulation of gene expression and establish cell identity. However, during cell division, the replication of the genetic material produces a global disorganization of chromatin structure. In this… read more here.
Keywords: cell; role chromatin; replication; chromatin ... See more keywords