Articles with "role chromothripsis" as a keyword



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Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gametes and Preimplantation Embryo.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7780-2_3

Abstract: The discovery of a new class of massive chromosomal rearrangement, baptized chromothripsis, in different cancers and congenital disorders has deeply modified our understanding on the genesis of complex genomic rearrangements. Several mechanisms, involving abortive apoptosis,… read more here.

Keywords: genesis complex; chromothripsis; chromothripsis genesis; potential role ... See more keywords