Role of Circular RNAs in the Pathogenesis of Cardiovascular Disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-019-09912-2
Abstract: Circular RNAs (circRNAs) are single-strand covalently closed circular noncoding RNAs that are endogenous transcripts generated from linear precursor mRNA through a backsplicing mechanism. With the development of high-throughput sequencing technology, a number of circRNAs have… read more here.
Keywords: circular rnas; pathogenesis cardiovascular; cardiovascular diseases; role circular ... See more keywords
The emerging role of circular RNAs in transcriptome regulation.
Sign Up to like & getrecommendations! Published in 2017 at "Genomics"
DOI: 10.1016/j.ygeno.2017.06.005
Abstract: Circular RNAs (circRNAs) are a recently discovered form of RNA that has been found to regulate mammalian transcription. CircRNAs are covalently closed, single-stranded transcripts produced from precursor mRNA. While initially circRNAs were considered to be… read more here.
Keywords: circular rnas; emerging role; role circular; expression ... See more keywords
Current status and potential role of circular RNAs in neurological disorders
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14724
Abstract: Given the importance of non‐coding RNAs in modulating normal brain functions and their implications in the treatment of neurological disorders, non‐coding RNA‐based diagnostic and therapeutic strategies have shown great clinical potential. Circular RNAs (circRNAs) have… read more here.
Keywords: circular rnas; current status; status potential; role circular ... See more keywords
Role of Circular RNAs in Preeclampsia
Sign Up to like & getrecommendations! Published in 2019 at "Disease Markers"
DOI: 10.1155/2019/7237495
Abstract: Circular RNAs (circRNAs) are noncoding RNAs characterized by circular covalently closed structures, which are generated by back-splicing. circRNA is more stable and conserved than linear RNA and exists in various organisms. Preeclampsia (PE), a common… read more here.
Keywords: rnas preeclampsia; role circular; circular rnas; etiology ... See more keywords
Role of Circular RNAs in Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Current medicinal chemistry"
DOI: 10.2174/0929867330666230531095850
Abstract: OBJECTIVES This study aims to summarize the current literature to demonstrate the importance of circular RNAs (circRNAs) in multiple aspects of prostate cancer (PCa) occurrence, progression, and treatment resistance and explore the potential role in… read more here.
Keywords: role; prostate cancer; circular rnas; role circular ... See more keywords
The role of circular RNAs in therapy resistance of patients with solid tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Personalized medicine"
DOI: 10.2217/pme-2020-0103
Abstract: Circular RNAs (circRNAs) are a type of single-stranded RNA molecules forming a covalently closed, continuous structure, lacking 5'-3' polarity and polyadenylated tails. Recent advances in high-throughput sequencing technologies have revealed that these molecules are abundant,… read more here.
Keywords: circular rnas; solid tumors; role circular; resistance ... See more keywords
The Role of Circular RNAs in Immune-Related Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00545
Abstract: Circular RNAs (circRNAs) are a novel class of RNAs with a covalently closed loop structure without a 3′ polyadenylation [poly-(A)] tail or a 5′ cap. They used to be considered as the occasional and useless… read more here.
Keywords: research; circular rnas; immune related; related diseases ... See more keywords
The emerging role of circular RNAs in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1137363
Abstract: Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease and the most common movement disorder. It involves a gradual loss of dopaminergic neurons in the substantia nigra. Although many studies have been conducted, the… read more here.
Keywords: role circular; disease; circular rnas; parkinson disease ... See more keywords
The Diagnostic and Therapeutic Role of Circular RNA HIPK3 in Human Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12102469
Abstract: Circular RNAs (circRNAs) are a class of noncoding RNAs with closed-loop of single-stranded RNA structure. Although most of the circRNAs do not directly encode proteins, emerging evidence suggests that circRNAs play a pivotal and complex… read more here.
Keywords: role circular; therapeutic role; circular rna; human diseases ... See more keywords
Exploring the Regulatory Role of Circular RNAs in Neurodegenerative Disorders
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20215477
Abstract: Circular RNAs (circRNAs) are a distinctive class of regulatory non-coding RNAs characterised by the presence of covalently closed ends. They are evolutionary conserved molecules, and although detected in different tissues, circRNAs resulted specifically enriched in… read more here.
Keywords: regulatory role; circular rnas; exploring regulatory; rnas neurodegenerative ... See more keywords
Role of Circular RNAs in Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810493
Abstract: Pulmonary fibrosis is a chronic progressive form of interstitial lung disease, characterized by the histopathological pattern of usual interstitial pneumonia. Apart from aberrant alterations of protein-coding genes, dysregulation of non-coding RNAs, including microRNAs, long non-coding… read more here.
Keywords: role circular; circular rnas; pulmonary fibrosis; rnas pulmonary ... See more keywords