Articles with "role circular" as a keyword



Role of Circular RNAs in the Pathogenesis of Cardiovascular Disease

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Published in 2020 at "Journal of Cardiovascular Translational Research"

DOI: 10.1007/s12265-019-09912-2

Abstract: Circular RNAs (circRNAs) are single-strand covalently closed circular noncoding RNAs that are endogenous transcripts generated from linear precursor mRNA through a backsplicing mechanism. With the development of high-throughput sequencing technology, a number of circRNAs have… read more here.

Keywords: circular rnas; pathogenesis cardiovascular; cardiovascular diseases; role circular ... See more keywords
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The emerging role of circular RNAs in transcriptome regulation.

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Published in 2017 at "Genomics"

DOI: 10.1016/j.ygeno.2017.06.005

Abstract: Circular RNAs (circRNAs) are a recently discovered form of RNA that has been found to regulate mammalian transcription. CircRNAs are covalently closed, single-stranded transcripts produced from precursor mRNA. While initially circRNAs were considered to be… read more here.

Keywords: circular rnas; emerging role; role circular; expression ... See more keywords

The dual role of circular RNAs in paclitaxel resistance: insights into molecular mechanisms and clinical implications.

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Published in 2025 at "Cell cycle"

DOI: 10.1080/15384101.2025.2575050

Abstract: ABSTRACT Paclitaxel is a widely used chemotherapeutic agent that plays a vital role in the treatment of various cancers, including breast, ovarian, and lung cancers. Despite its success, the development of resistance significantly limits its… read more here.

Keywords: paclitaxel resistance; resistance; role circular; molecular mechanisms ... See more keywords
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Current status and potential role of circular RNAs in neurological disorders

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Published in 2019 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.14724

Abstract: Given the importance of non‐coding RNAs in modulating normal brain functions and their implications in the treatment of neurological disorders, non‐coding RNA‐based diagnostic and therapeutic strategies have shown great clinical potential. Circular RNAs (circRNAs) have… read more here.

Keywords: circular rnas; current status; status potential; role circular ... See more keywords

Role of Circular RNAs in Preeclampsia

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Published in 2019 at "Disease Markers"

DOI: 10.1155/2019/7237495

Abstract: Circular RNAs (circRNAs) are noncoding RNAs characterized by circular covalently closed structures, which are generated by back-splicing. circRNA is more stable and conserved than linear RNA and exists in various organisms. Preeclampsia (PE), a common… read more here.

Keywords: rnas preeclampsia; role circular; circular rnas; etiology ... See more keywords

The Role of Circular Economy in Driving Economic Growth: Evidence from EU Countries

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Published in 2024 at "SAGE Open"

DOI: 10.1177/21582440241240624

Abstract: The transition to a circular economy has become an important topic in thinking about the sustainable future of humanity. An important and often disputed point in the academic debate on this topic is the relationship… read more here.

Keywords: per capita; economy; role circular; circular economy ... See more keywords

Role of Circular RNAs in Prostate Cancer.

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Published in 2023 at "Current medicinal chemistry"

DOI: 10.2174/0929867330666230531095850

Abstract: OBJECTIVES This study aims to summarize the current literature to demonstrate the importance of circular RNAs (circRNAs) in multiple aspects of prostate cancer (PCa) occurrence, progression, and treatment resistance and explore the potential role in… read more here.

Keywords: role; prostate cancer; circular rnas; role circular ... See more keywords
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The role of circular RNAs in therapy resistance of patients with solid tumors.

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Published in 2020 at "Personalized medicine"

DOI: 10.2217/pme-2020-0103

Abstract: Circular RNAs (circRNAs) are a type of single-stranded RNA molecules forming a covalently closed, continuous structure, lacking 5'-3' polarity and polyadenylated tails. Recent advances in high-throughput sequencing technologies have revealed that these molecules are abundant,… read more here.

Keywords: circular rnas; solid tumors; role circular; resistance ... See more keywords

The Role of Circular RNAs in Immune-Related Diseases

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Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.00545

Abstract: Circular RNAs (circRNAs) are a novel class of RNAs with a covalently closed loop structure without a 3′ polyadenylation [poly-(A)] tail or a 5′ cap. They used to be considered as the occasional and useless… read more here.

Keywords: research; circular rnas; immune related; related diseases ... See more keywords

The emerging role of circular RNAs in Parkinson’s disease

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Published in 2023 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2023.1137363

Abstract: Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease and the most common movement disorder. It involves a gradual loss of dopaminergic neurons in the substantia nigra. Although many studies have been conducted, the… read more here.

Keywords: role circular; disease; circular rnas; parkinson disease ... See more keywords

The Role of Circular RNA in the Progression of Gliomas and Its Potential Clinical Applications

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Published in 2025 at "Biology"

DOI: 10.3390/biology14070795

Abstract: Simple Summary The treatment outcomes and prognosis for glioma patients remain unsatisfactory, and a comprehensive understanding of the mechanisms underlying glioma development and progression is essential for improving therapeutic strategies. It has been demonstrated that… read more here.

Keywords: progression; role circular; progression gliomas; gliomas potential ... See more keywords