Mitochondria, mitophagy, and the role of deubiquitinases as novel therapeutic targets in liver pathology
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30312
Abstract: Liver diseases such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), fibrosis, and hepatocellular carcinoma (HCC) have increased over the past few decades due to the absence or ineffective therapeutics. Recently, it has been… read more here.
Keywords: mitochondria mitophagy; role deubiquitinases; mitophagy role; role ... See more keywords
The Role of Deubiquitinases in Oncovirus and Host Interactions
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DOI: 10.1155/2019/2128410
Abstract: Infection-related cancer comprises one-sixth of the global cancer burden. Oncoviruses can directly or indirectly contribute to tumorigenesis. Ubiquitination is a dynamic and reversible posttranslational modification that participates in almost all cellular processes. Hijacking of the… read more here.
Keywords: oncovirus host; deubiquitinases oncovirus; host; host interactions ... See more keywords
The emerging role of Deubiquitinases (DUBs) in parasites: A foresight review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.985178
Abstract: Before the discovery of the proteasome complex, the lysosomes with acidic proteases and caspases in apoptotic pathways were thought to be the only pathways for the degradation of damaged, unfolded, and aged proteins. However, the… read more here.
Keywords: role deubiquitinases; role; review; parasite dubs ... See more keywords
The role of deubiquitinases in cardiovascular diseases: mechanisms and therapeutic implications
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2025.1582049
Abstract: Cardiovascular diseases (CVDs) have become the leading cause of death globally, surpassing infectious diseases and other chronic illnesses. The incidence and mortality rates of CVDs are rising worldwide, posing a key challenge in public health.… read more here.
Keywords: diseases mechanisms; role deubiquitinases; role; mechanisms therapeutic ... See more keywords
The Emerging Role of Deubiquitinases in Cell Death
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DOI: 10.3390/biom12121825
Abstract: Regulated cell death (RCD) is a signal-controlled process that not only eliminates infected, damaged, or aged cells but is also implicated in a variety of pathological conditions. The process of RCD is regulated by intracellular… read more here.
Keywords: cell death; emerging role; deubiquitinases cell; role deubiquitinases ... See more keywords