Upstream regulators of phosphoinositide 3‐kinase and their role in diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28215
Abstract: Phosphoinositide 3‐kinase (PI3K), a crucial signaling molecule, is regulated by various upstream regulators. Traditionally, receptor tyrosine kinases and G protein‐coupled receptor are regarded as its principle upstream regulators; however, recent reports have indicated that spleen… read more here.
Keywords: kinase role; regulators phosphoinositide; upstream regulators; role diseases ... See more keywords
An update on Ym1 and its immunoregulatory role in diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.891220
Abstract: Ym1 is a rodent-specific chitinase-like protein (CLP) lacking catalytic activity, whose cellular origins are mainly macrophages, neutrophils and other cells. Although the detailed function of Ym1 remains poorly understood, Ym1 has been generally recognized as… read more here.
Keywords: ym1; immunoregulatory role; ym1 immunoregulatory; role diseases ... See more keywords
Regulation of iNOS on Immune Cells and Its Role in Diseases
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19123805
Abstract: In recent years, there have been many studies on the function of nitric oxide synthase (NOS) in experimental animals and humans. This review analyzes and explores the relationship between inducible nitric oxide synthase (iNOS) and… read more here.
Keywords: research; regulation inos; role diseases; immune cells ... See more keywords
Cyclin-Dependent Kinases (CDK) and Their Role in Diseases Development–Review
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22062935
Abstract: Cyclin-dependent kinases (CDKs) are involved in many crucial processes, such as cell cycle and transcription, as well as communication, metabolism, and apoptosis. The kinases are organized in a pathway to ensure that, during cell division,… read more here.
Keywords: kinases cdk; dependent kinases; cyclin dependent; role diseases ... See more keywords