The critical role of epigenetic mechanisms involved in nanotoxicology.
Sign Up to like & getrecommendations! Published in 2022 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1789
Abstract: Over the past decades, nanomaterials (NMs) have been widely applied in the cosmetic, food, engineering, and medical fields. Along with the prevalence of NMs, the toxicological characteristics exhibited by these materials on health and the… read more here.
Keywords: epigenetic alterations; methylation; role; role epigenetic ... See more keywords
The Essential Role of Epigenetic Modifications in Neurodegenerative Diseases with Dyskinesia.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-021-01133-z
Abstract: Epigenetics play an essential role in the occurrence and improvement of many diseases. Evidence shows that epigenetic modifications are crucial to the regulation of gene expression. DNA methylation is closely linked to embryonic development in… read more here.
Keywords: epigenetic modifications; modifications neurodegenerative; essential role; neurodegenerative diseases ... See more keywords
Role of epigenetic abnormalities and intervention in obstructive sleep apnea target organs.
Sign Up to like & getrecommendations! Published in 2022 at "Chinese medical journal"
DOI: 10.1097/cm9.0000000000002080
Abstract: ABSTRACT Obstructive sleep apnea (OSA) is a common condition that has considerable impacts on human health. Epigenetics has become a rapidly developing and exciting area in biology, and it is defined as heritable alterations in… read more here.
Keywords: sleep apnea; abnormalities intervention; epigenetic abnormalities; obstructive sleep ... See more keywords
Role of epigenetic mechanisms regulated by enhancers and long noncoding RNAs in cardiovascular disease.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Cardiology"
DOI: 10.1097/hco.0000000000000728
Abstract: PURPOSE OF REVIEW Hyperlipidemia, hypertension, diabetes and related metabolic disorders increase the risk for cardiovascular disease (CVD). Despite significant progress in the identification of key mechanisms and genetic polymorphisms linked to various CVDs, the rates… read more here.
Keywords: cardiovascular disease; role epigenetic; long noncoding; noncoding rnas ... See more keywords
The Critical Role of Epigenetic Regulation in Developmental Programming of Higher Organisms
Sign Up to like & getrecommendations! Published in 2019 at "Current Genomics"
DOI: 10.2174/138920292006191206141546
Abstract: In the last years, research efforts have been focused on the understanding of the evolutionary mechanisms linked to the control of the transcriptional activity and developmental processes. The study of developmental mechanisms has advanced significance… read more here.
Keywords: critical role; developmental; developmental programming; role epigenetic ... See more keywords
Harnessing the role of epigenetic histone modification in targeting head and neck squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Epigenomics"
DOI: 10.2217/epi-2020-0348
Abstract: Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent form of cancer worldwide. Despite advancements made in treatment strategies, the fatality rate of HNSCC is very high. An accumulating body of evidence… read more here.
Keywords: cell carcinoma; head neck; role; squamous cell ... See more keywords
The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.877263
Abstract: It has been widely demonstrated by numerous preclinical studies and clinical trials that the neonates receiving repeated or long-time general anesthesia (GA) could develop prolonged cognitive dysfunction. However, the definite mechanism remains largely unknown. Epigenetics,… read more here.
Keywords: general anesthesia; anesthesia; epigenetic modifications; neurotoxicity ... See more keywords
Stress Memory in Seagrasses: First Insight Into the Effects of Thermal Priming and the Role of Epigenetic Modifications
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.00494
Abstract: While thermal priming and the relative role of epigenetic modifications have been widely studied in terrestrial plants, their roles remain unexplored in seagrasses so far. Here, we experimentally compared the ability of two different functional… read more here.
Keywords: role epigenetic; epigenetic modifications; stress memory; thermal priming ... See more keywords
The Role of Epigenetic Modifications in Abdominal Aortic Aneurysm Pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020172
Abstract: Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high morbidity and mortality in the setting of acute rupture. Recently, advances in surgical and endovascular repair of AAA have been achieved; however, pharmaceutical therapies… read more here.
Keywords: abdominal aortic; epigenetic modifications; aortic aneurysm; modifications abdominal ... See more keywords
The Role of Epigenetic Modifications in Human Cancers and the Use of Natural Compounds as Epidrugs: Mechanistic Pathways and Pharmacodynamic Actions
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12030367
Abstract: Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal cells. The mechanistic understanding of the pathways involved in tumor transformation has implicated a priori predominance of epigenetic perturbations and a… read more here.
Keywords: cancers use; use natural; modifications human; human cancers ... See more keywords
The Role of Epigenetic Modifications in Late Complications in Type 1 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13040705
Abstract: Type 1 diabetes is a chronic autoimmune disease in which the destruction of pancreatic β cells leads to hyperglycemia. The prevention of hyperglycemia is very important to avoid or at least postpone the development of… read more here.
Keywords: late complications; epigenetic modifications; complications type; type diabetes ... See more keywords