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Published in 2020 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22414
Abstract: Environmental endocrine disruptors (EEDs) seriously endanger human health by interfering with the normal function of reproductive systems. In males, EEDs can affect sperm formation and semen quality as well spermatogenesis, ultimately reducing fertility. In females,…
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Keywords:
toxicity;
endocrine disruptors;
reproductive toxicity;
role epigenetics ... See more keywords
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Published in 2020 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-020-00976-8
Abstract: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and heterogeneous inflammatory disease. The underlying epigenetic mechanisms and treatment of CRSwNP are partially understood. Of the different epigenetic changes in CRSwNP, histone deacetylases (HDACs), methylation…
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Keywords:
chronic sinusitis;
mir;
crswnp;
epigenetics chronic ... See more keywords
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Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.113973
Abstract: The epidemic of obesity has become pandemic, putting a significant burden on the world's healthcare system. While the heritability of the disease is high, all the identified genetic variants associated to obesity account for a…
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Keywords:
development obesity;
epigenetics development;
pharmacology;
obesity ... See more keywords
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Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.144049
Abstract: The role of epigenetics in development has garnered attention in recent years due to their ability to modulate the embryonic developmental gene expression in response to the environmental cues. The epigenetic mechanisms - DNA methylation,…
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Keywords:
epigenetics zebrafish;
zebrafish development;
role epigenetics;
development ... See more keywords
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Published in 2017 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000355
Abstract: Purpose of review The purpose of this review is to provide an update of recent advances in the established role of different layers of epigenetic control mechanism that are used by joint cells to ensure…
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Keywords:
control;
epigenetic control;
epigenetics osteoarthritis;
role ... See more keywords
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Published in 2021 at "Applied Sciences"
DOI: 10.3390/app11115269
Abstract: The aims of this systematic review were to identify and synthesize the evidence for an association in DNA methylation/histone modifications between periodontal diseases and systemic diseases/smoking. Electronic database searches using relevant search terms in PubMed,…
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Keywords:
systemic diseases;
role epigenetics;
systematic review;
periodontitis ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094873
Abstract: Primary Biliary Cholangitis (PBC) is a rare autoimmune disease of the liver, affecting mostly females. There is evidence that epigenetic changes have a pathogenic role in PBC. Epigenetic modifications are related to methylation of CpG…
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Keywords:
biliary cholangitis;
role epigenetics;
primary biliary;
pbc ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315218
Abstract: Neurodegenerative disorders are characterized by the progressive loss of central and/or peripheral nervous system neurons. Within this context, neuroinflammation comes up as one of the main factors linked to neurodegeneration progression. In fact, neuroinflammation has…
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Keywords:
role epigenetics;
neuroinflammatory driven;
driven diseases;
epigenetics neuroinflammatory ... See more keywords
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Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2017.8001
Abstract: Chronic rhinosinusitis (CRS) is a highly prevalent disease characterized by mucosal inflammation of the nose and paranasal sinuses. CRS can be divided into two main categories, CRS with nasal polyps (NPs; CRSwNP) and CRS without…
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Keywords:
nasal polyps;
chronic rhinosinusitis;
epigenetics pathogenesis;
role epigenetics ... See more keywords