Role of ferroptosis in gastrointestinal tumors: From mechanisms to therapies
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11804
Abstract: Ferroptosis is an iron‐dependent nonapoptotic regulated cell death, which is mainly caused by an abnormal increase in lipid oxygen free radicals and an imbalance in redox homeostasis. Recently, ferroptosis has been shown to have implications… read more here.
Keywords: ferroptosis gastrointestinal; role ferroptosis; ferroptosis; tumors mechanisms ... See more keywords
The role of ferroptosis in the development of acute and chronic kidney diseases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30901
Abstract: Ferroptosis, a novel form of regulated cell death, is characterized by imbalance of intracellular iron and redox systems, resulting from overgeneration of toxic lipid peroxidation products. In recent years, the verified crucial role of ferroptosis… read more here.
Keywords: kidney; chronic kidney; role ferroptosis; acute chronic ... See more keywords
Role of ferroptosis in neurological diseases
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.135614
Abstract: Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD) characterized by iron-dependent accumulation of lipid peroxides which leads to oxidative stress and cell death. Recent studies have indicated that ferroptosis plays an… read more here.
Keywords: ferroptosis neurological; pathology; ferroptosis; neurological diseases ... See more keywords
Role of ferroptosis in radiation-induced soft tissue injury
Sign Up to like & getrecommendations! Published in 2024 at "Cell Death Discovery"
DOI: 10.1038/s41420-024-02003-5
Abstract: Ionizing radiation has been pivotal in cancer therapy since its discovery. Despite its therapeutic benefits, IR causes significant acute and chronic complications due to DNA damage and the generation of reactive oxygen species, which harm… read more here.
Keywords: radiation; ferroptosis; role ferroptosis; cell death ... See more keywords
Exploring the role of ferroptosis in esophageal cancer: mechanisms and therapeutic implications
Sign Up to like & getrecommendations! Published in 2025 at "Cell Death Discovery"
DOI: 10.1038/s41420-025-02696-2
Abstract: With the development of medical and health care, esophageal cancer (EC) has become a disease of concern to the scientific research community. At present, among all treatment regimens for EC, surgical resection is conducive to… read more here.
Keywords: ferroptosis esophageal; exploring role; cancer; ferroptosis ... See more keywords
An update on the role of ferroptosis in ischemic stroke: from molecular pathways to Neuroprotection
Sign Up to like & getrecommendations! Published in 2024 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2024.2446319
Abstract: ABSTRACT Introduction Ischemic stroke (IS), a major cause of mortality and disability worldwide, remains a significant healthcare challenge due to limited therapeutic options. Ferroptosis, a distinct iron-dependent form of regulated cell death characterized by lipid… read more here.
Keywords: ischemic stroke; ferroptosis ischemic; update role; ferroptosis ... See more keywords
The Emerging Role of Ferroptosis in Sepsis.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2021.1072
Abstract: Ferroptosis is a novel form of cell death characterized by the iron-dependent accumulation of lipid peroxides and is different from other types of cell death. The mechanisms of ferroptosis are discussed in the review, including… read more here.
Keywords: sepsis; cell death; role ferroptosis; emerging role ... See more keywords
Role of ferroptosis in neuroimmunity and neurodegeneration in multiple sclerosis revealed by multi‐omics data
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.18396
Abstract: Previous studies have found that ferroptosis plays an important role in a variety of neurological diseases. However, the precise role of ferroptosis in the multiple sclerosis patients remains uncertain. We defined and validated a computational… read more here.
Keywords: role ferroptosis; ferroptosis; multiple sclerosis; ferroptosis score ... See more keywords
The Role of Ferroptosis in Mediating Muscle Atrophy under Hyperglycemic Conditions
Sign Up to like & getrecommendations! Published in 2025 at "Physiology"
DOI: 10.1152/physiol.2025.40.s1.0854
Abstract: Objective: This study investigates the potential role of ferroptosis, a recently identified form of cell death mechanism, in diabetic myopathy. We hypothesized that ferroptosis plays a role in modulating the morphology and size of C2C12… read more here.
Keywords: physiology; muscle; ferroptosis; expression ... See more keywords
The emerging role of ferroptosis in the pathological development and progression of sepsis
Sign Up to like & getrecommendations! Published in 2025 at "Military Medical Research"
DOI: 10.1186/s40779-025-00665-5
Abstract: Ferroptosis, a form of iron-dependent regulated cell death (RCD), is emerging as a critical mechanism in the pathogenesis and progression of sepsis. This review highlights the intricate molecular pathways and hallmark features of ferroptosis, including… read more here.
Keywords: progression sepsis; ferroptosis; injury; role ferroptosis ... See more keywords
Exploring the role of ferroptosis-related genes as biomarkers in acute kidney injury
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0307472
Abstract: Introduction Acute kidney injury (AKI) is a severe condition with high morbidity and mortality. Innovative biomarkers and treatments are essential for improving patient outcomes. This study aims to investigate the role of ferroptosis-related genes (FRGs)… read more here.
Keywords: ferroptosis related; related genes; ferroptosis; role ferroptosis ... See more keywords