TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming.
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DOI: 10.1021/acschemneuro.2c00119
Abstract: As one of the key injury incidents, tissue acidosis in the brain occurs very quickly within several minutes upon the onset of ischemic stroke. Glutamate, an excitatory amino acid inducing neuronal excitotoxicity, has been reported… read more here.
Keywords: role glutamate; injury; intracellular acidification; rapid intracellular ... See more keywords
Testing the Role of Glutamate NMDA Receptors in Peripheral Trigeminal Nociception Implicated in Migraine Pain
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DOI: 10.3390/ijms23031529
Abstract: The pro-nociceptive role of glutamate in the CNS in migraine pathophysiology is well established. Glutamate, released from trigeminal afferents, activates second order nociceptive neurons in the brainstem. However, the function of peripheral glutamate receptors in… read more here.
Keywords: glutamate; role glutamate; migraine pain; nmda receptors ... See more keywords