Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope
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DOI: 10.1002/psc.3229
Abstract: MUC1 is a membrane glycoprotein, which in adenocarninomas is overexpressed and exhibits truncated O‐glycosylation. Overexpression and altered glycosylation make MUC1 into a candidate for immunotherapy. Monoclonal antibodies directed against MUC1 frequently bind an immunodominant epitope… read more here.
Keywords: immunodominant epitope; role glycosylation; muc1; glycosylation ... See more keywords
Role of N-Glycosylation in FcγRIIIa interaction with IgG
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.987151
Abstract: Immunoglobulins G (IgG) and their Fc gamma receptors (FcγRs) play important roles in our immune system. The conserved N-glycan in the Fc region of IgG1 impacts interaction of IgG with FcγRs and the resulting effector… read more here.
Keywords: interaction igg; glycosylation; role glycosylation; riiia ... See more keywords