Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental biology"
DOI: 10.1016/j.ydbio.2021.01.012
Abstract: Proliferation and differentiation of vocal fold epithelial cells during embryonic development is poorly understood. We examined the role of Hippo signaling, a vital pathway known for regulating organ size, in murine laryngeal development. Conditional inactivation… read more here.
Keywords: role hippo; lats1 lats2; vocal fold; inactivation ... See more keywords
The role of the Hippo pathway in autophagy in the heart.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular research"
DOI: 10.1093/cvr/cvac014
Abstract: The Hippo pathway, an evolutionarily conserved signaling mechanism, controls organ size and tumorigenesis. Increasing lines of evidence suggest that autophagy, an important mechanism of lysosome-mediated cellular degradation, is regulated by the Hippo pathway, which thereby… read more here.
Keywords: hippo pathway; autophagy heart; role hippo; pathway autophagy ... See more keywords
The role of Hippo pathway in ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1107505
Abstract: The role of Hippo pathway in ferroptosis The Hippo pathway is mainly composed of mammalian serine/threonine (Ste20)like kinases 1/2 (MST1/2), large tumor suppressor 1/2 (LATS1/2), and transcriptional coactivator Yes-associated protein (YAP), and is closely related… read more here.
Keywords: pathway ferroptosis; hippo pathway; role hippo; hippo ... See more keywords