Role of HMGB1 in Vitiligo: Current Perceptions and Future Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Clinical, Cosmetic and Investigational Dermatology"
DOI: 10.2147/ccid.s381432
Abstract: Abstract Vitiligo is a chronic depigmenting disorder of the skin and mucosa caused by the destruction of epidermal melanocytes. Although the exact mechanism has not been elucidated, studies have shown that oxidative stress plays an… read more here.
Keywords: hmgb1 vitiligo; role; role hmgb1; oxidative stress ... See more keywords
The Role of HMGB1 in Rheumatic Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.815257
Abstract: HMGB1, a highly conserved non-histone nuclear protein, is widely expressed in mammalian cells. HMGB1 in the nucleus binds to the deoxyribonucleic acid (DNA) to regulate the structure of chromosomes and maintain the transcription, replication, DNA… read more here.
Keywords: hmgb1; role hmgb1; hmgb1 rheumatic; rheumatic diseases ... See more keywords
Role of HMGB1/TLR4 and IL-1β/IL-1R1 Signaling Pathways in Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.904225
Abstract: Epilepsy is a chronic disorder of the nervous system characterized by recurrent seizures. Inflammation is one of the six major causes of epilepsy, and its role in the pathogenesis of epilepsy is gaining increasing attention.… read more here.
Keywords: role hmgb1; hmgb1 tlr4; tlr4 1r1; epilepsy ... See more keywords
Role of HMGB1 in Cutaneous Melanoma: State of the Art
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DOI: 10.3390/ijms23169327
Abstract: High-mobility Group Box 1 (HMGB1) is a nuclear protein that plays a key role in acute and chronic inflammation. It has already been studied in several diseases, among them melanoma. Indeed, HMGB1 is closely associated… read more here.
Keywords: role; role hmgb1; hmgb1 cutaneous; therapy ... See more keywords