The role of hypoxia‐inducible factor‐2 alpha in angiogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26805
Abstract: Angiogenesis is a key enabling feature of mammalian embryonic development and tumor progression, which provides oxygen and nutrients that are required for vessel growth and tumor cell growth, respectively. Hypoxia is a driver of this… read more here.
Keywords: angiogenesis; role hypoxia; inducible factor; factor alpha ... See more keywords
Low vascularization of the nephrogenic zone of the fetal kidney suggests a major role for hypoxia in human nephrogenesis
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1630-y
Abstract: CD31 reactivity is generally utilized as a marker of endothelial cells. CD31 immunoreactivity in the developing human kidney revealed that fetal glomerular capillary endothelial cells change their immunohistochemical phenotype during maturation. The aim of this… read more here.
Keywords: nephrogenic zone; role hypoxia; cd31; major role ... See more keywords
Role of hypoxia-induced exosomes in tumor biology
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0869-y
Abstract: PurposeHypoxia is a major regulator of angiogenesis and always influences the release of exosomes in various types of tumors. The present review aimed to assess the role of hypoxia-induced exosomes in the tumor biology.MethodsThe relevant… read more here.
Keywords: role hypoxia; biology; hypoxia; exosomes tumor ... See more keywords
The role of hypoxia in the development and progression of endometriosis.
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction"
DOI: 10.1530/rep-20-0267
Abstract: Endometriosis is a benign gynecological disease that affects about 10% women of reproductive age. Patients with endometriosis suffer from long-term coexistence with dysmenorrhea, dyspareunia, and even infertility, which severely reduces life quality. So far, surgical… read more here.
Keywords: endometriosis; development progression; progression endometriosis; role hypoxia ... See more keywords
Role of Hypoxia in the Interferon Response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.821816
Abstract: In solid tumors, as the tumor grows and the disease progresses, hypoxic regions are often generated, but in contrast to most normal cells which cannot survive under these conditions, tumour cells adapt to hypoxia by… read more here.
Keywords: hypoxia interferon; interferon response; role hypoxia; hypoxia ... See more keywords
Editorial: Role of hypoxia-inducible factors in metabolic immune cell adaptation during sepsis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1194504
Abstract: COPYRIGHT © 2023 del Fresno, Schulte and LópezCollazo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted,… read more here.
Keywords: metabolic immune; inducible factors; role hypoxia; hypoxia inducible ... See more keywords
The Role of Hypoxia and the Immune System in Tumor Radioresistance
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DOI: 10.3390/cancers11101555
Abstract: Radiotherapy is given to a majority of patients with cancer, and remains one of the most (cost)effective treatment options available [...]. read more here.
Keywords: tumor radioresistance; role hypoxia; immune system; hypoxia immune ... See more keywords
The Role of Hypoxia and Cancer Stem Cells in Development of Glioblastoma
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DOI: 10.3390/cancers15092613
Abstract: Simple Summary As one of most malignant tumors in brain, glioblastoma (GBM) is lack of effective treatment and the prognosis of GBM patients is still very poor despite accumulated progresses. Hypoxia is an essential factor… read more here.
Keywords: glioblastoma; development; role hypoxia; hypoxia ... See more keywords
Necrotizing Enterocolitis: The Role of Hypoxia, Gut Microbiome, and Microbial Metabolites
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032471
Abstract: Necrotizing enterocolitis (NEC) is a life-threatening disease that predominantly affects very low birth weight preterm infants. Development of NEC in preterm infants is accompanied by high mortality. Surgical treatment of NEC can be complicated by… read more here.
Keywords: role; enterocolitis role; necrotizing enterocolitis; role hypoxia ... See more keywords