Is there a role for immunotherapy in malignant pleural mesothelioma?
Sign Up to like & getrecommendations! Published in 2018 at "Medical Oncology"
DOI: 10.1007/s12032-018-1156-x
Abstract: Malignant pleural mesothelioma (MPM) is a very aggressive malignancy, mainly caused by asbestos exposure. Patients with MPM have a poor prognosis that remained substantially unchanged in the last few years and limited effective therapeutic options… read more here.
Keywords: pleural mesothelioma; role immunotherapy; malignant pleural;
Tumour-infiltrating lymphocytes and the emerging role of immunotherapy in breast cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Pathology"
DOI: 10.1016/j.pathol.2016.10.010
Abstract: Breast cancer has not previously been considered a highly immunogenic cancer. Observations of tumour-infiltrating lymphocytes (TILs) in and around neoplastic cells in tumour samples, and associations with improved pathological complete response and clinical survival end… read more here.
Keywords: cancer; emerging role; role immunotherapy; breast cancer ... See more keywords
Role of immunotherapy in Ewing sarcoma
Sign Up to like & getrecommendations! Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-000653
Abstract: Ewing sarcoma (ES) is thought to arise from mesenchymal stem cells and is the second most common bone sarcoma in pediatric patients and young adults. Given the dismal overall outcomes and very intensive therapies used,… read more here.
Keywords: role immunotherapy; immunotherapy; ewing sarcoma; antigen ... See more keywords
The emerging role of immunotherapy in biliary tract cancer: a review of new evidence and predictive biomarkers.
Sign Up to like & getrecommendations! Published in 2022 at "Immunotherapy"
DOI: 10.2217/imt-2021-0257
Abstract: Biliary tract cancers (BTCs) are frequently diagnosed in advanced stages and are highly lethal. Immunotherapy may play a role in the treatment of these patients. Promising results come from monotherapy or combination therapy studies in… read more here.
Keywords: immunotherapy; role; role immunotherapy; emerging role ... See more keywords
The biological role and immunotherapy of gangliosides and GD3 synthase in cancers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1076862
Abstract: Gangliosides are a large subfamily of glycosphingolipids that broadly exist in the nervous system and interact with signaling molecules in the lipid rafts. GD3 and GD2 are two types of disialogangliosides (GDs) that include two… read more here.
Keywords: gd3 gd2; gd3 synthase; role immunotherapy; biological role ... See more keywords
Dendritic Cells and Their Role in Immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00924
Abstract: Despite significant advances in the field of cancer immunotherapy, the majority of patients still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have long been a focus of cancer immunotherapy… read more here.
Keywords: role immunotherapy; immunotherapy; dendritic cells; immune response ... See more keywords
Defining the Role of Immunotherapy in the Curative Treatment of Locoregionally Advanced Head and Neck Cancer: Promises, Challenges, and Opportunities
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.738626
Abstract: Recent advancements in the development of immunotherapies have raised the hope for patients with locally-advanced HNSCC (LA-HNSCC) to achieve improved oncologic outcomes without the heavy burden of treatment-related morbidity. While there are several ongoing late… read more here.
Keywords: role immunotherapy; immunotherapy; immunotherapy curative; curative treatment ... See more keywords
The Role of Immunotherapy in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Current Oncology"
DOI: 10.3390/curroncol29100541
Abstract: Pancreatic adenocarcinoma remains one of the most lethal cancers globally, with a significant need for improved therapeutic options. While the recent breakthroughs of immunotherapy through checkpoint inhibitors have dramatically changed treatment paradigms in other malignancies… read more here.
Keywords: pancreatic cancer; role immunotherapy; immunotherapy pancreatic; cancer ... See more keywords
An Expanding Role for Immunotherapy in Colorectal Cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the National Comprehensive Cancer Network : JNCCN"
DOI: 10.6004/jnccn.2017.0037
Abstract: Colorectal cancer (CRC) is a leading cause of cancer-related mortality in the United States. Response rates to second- and third-line therapy for metastatic CRC (mCRC) remain low, and immunotherapy is an attractive strategy for treatment… read more here.
Keywords: role immunotherapy; colorectal cancer; crc; cancer ... See more keywords
Role of Immunotherapy in Triple-Negative Breast Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the National Comprehensive Cancer Network : JNCCN"
DOI: 10.6004/jnccn.2020.7554
Abstract: Immune checkpoint inhibitors (ICIs) have led to durable clinical remissions in many metastatic cancers. However, the single-agent efficacy of ICIs in breast cancer is low, including in triple-negative breast cancer (TNBC), which has several key… read more here.
Keywords: negative breast; role immunotherapy; breast cancer; cancer ... See more keywords
Evolving Role of Immunotherapy in Recurrent Metastatic Head and Neck Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the National Comprehensive Cancer Network : JNCCN"
DOI: 10.6004/jnccn.2020.7590
Abstract: Immunotherapy has revolutionized cancer treatment in the past 2 decades, mostly with immune checkpoint blockade approaches. In squamous cell carcinoma of the head and neck (SCCHN), the initial efficacy of immunotherapy was observed in patients… read more here.
Keywords: recurrent metastatic; role immunotherapy; immunotherapy; treatment ... See more keywords