The immunometabolic role of indoleamine 2 3-dioxygenase in atherosclerotic cardiovascular disease: immune homeostatic mechanisms in the artery wall.
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular research"
DOI: 10.1093/cvr/cvz067
Abstract: Coronary heart disease (CHD) and stroke, the two most common cardiovascular diseases (CVDs) worldwide, are triggered by complications of atherosclerosis. Atherosclerotic plaques are triggered by a maladaptive immune response initiated by accumulation of lipids in… read more here.
Keywords: artery wall; role indoleamine; disease; immunometabolic role ... See more keywords
Role of the indoleamine-2,3-dioxygenase/kynurenine pathway of tryptophan metabolism in behavioral alterations in a hepatic encephalopathy rat model
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-017-1037-9
Abstract: BackgroundThis study aims to explore the role of indoleamine-2,3-dioxygenase (IDO)/kynurenine (KYN) pathway of tryptophan (TRY) metabolism in behavioral alterations observed in hepatic encephalopathy (HE) rats.MethodsExpression levels of proinflammatory cytokines were tested by QT-PCR and ELISA,… read more here.
Keywords: role indoleamine; metabolism; pathway tryptophan; metabolism behavioral ... See more keywords