The Role of Innate Immune Cells in Nonalcoholic Steatohepatitis
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30506
Abstract: Inflammation and metabolic dysfunction are hallmarks of nonalcoholic steatohepatitis (NASH), which is one of the fastest‐growing liver diseases worldwide. Emerging evidence indicates that innate immune mechanisms are pivotal drivers of inflammation and other pathological manifestations… read more here.
Keywords: nonalcoholic steatohepatitis; cells nonalcoholic; role innate; immune cells ... See more keywords
The role of innate lymphoid cells in health and disease
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DOI: 10.1002/jcp.26250
Abstract: Innate lymphoid cells (ILCs) are kind of innate immune cells which can be divided into three main subsets according to their cytokine release profile, transcription factors, and surface markers. ILCs affect the initial stages of… read more here.
Keywords: innate; role innate; disease; innate lymphoid ... See more keywords
Role of Innate Genes in HIV Replication.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_29
Abstract: Cells use an elaborate innate immune surveillance and defense system against virus infections. Here, we discuss recent studies that reveal how HIV-1 is sensed by the innate immune system. Furthermore, we present mechanisms on the… read more here.
Keywords: innate; innate genes; genes hiv; innate response ... See more keywords
Role of innate inflammation in traumatic brain injury
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DOI: 10.1007/s10072-020-05002-3
Abstract: Traumatic brain injury is one of the leading causes of morbidity and mortality throughout the world. Its increasing incidence, in addition to its fundamental role in the development of neurodegenerative disease, proves especially concerning. Despite… read more here.
Keywords: traumatic brain; role innate; brain; brain injury ... See more keywords
The role of innate immune genes in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000000911
Abstract: Purpose of review The aim of this study was to provide an update on the role of the innate immune system and neuroinflammation in the pathogenesis of Alzheimer's disease, with an emphasis on microglial receptors… read more here.
Keywords: innate immune; alzheimer disease; role innate; disease ... See more keywords
Immunopathogenesis of endometriosis: An overview of the role of innate and adaptive immune cells and their mediators
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13537
Abstract: Endometriosis is a chronic inflammatory disease associated with the growth and proliferation of endometrial‐like tissues outside the uterus. Although the exact etiology and mechanism of the pathogenesis of the disease have not been fully elucidated,… read more here.
Keywords: overview role; immunopathogenesis endometriosis; endometriosis overview; endometriosis ... See more keywords
The role of innate immunity in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Reviews"
DOI: 10.1111/imr.12896
Abstract: The amyloid hypothesis has dominated Alzheimer's disease (AD) research for almost 30 years. This hypothesis hinges on the predominant clinical role of the amyloid beta (Aβ) peptide in propagating neurofibrillary tangles (NFTs) and eventual cognitive… read more here.
Keywords: alzheimer disease; innate immunity; role innate;
Insights From Pre-Clinical and Clinical Studies on the Role of Innate Inflammation in Atherosclerosis Regression
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2018.00032
Abstract: Atherosclerosis, the underlying cause of coronary artery (CAD) and other cardiovascular diseases, is initiated by macrophage-mediated immune responses to lipoprotein and cholesterol accumulation in artery walls, which result in the formation of plaques. Unlike at… read more here.
Keywords: clinical studies; regression; inflammation; role innate ... See more keywords
Daclizumab: Mechanisms of Action, Therapeutic Efficacy, Adverse Events and Its Uncovering the Potential Role of Innate Immune System Recruitment as a Treatment Strategy for Relapsing Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Biomedicines"
DOI: 10.3390/biomedicines7010018
Abstract: Daclizumab (DAC) is a humanized, monoclonal antibody that blocks CD25, a critical element of the high-affinity interleukin-2 receptor (IL-2R). DAC HYP blockade of CD25 inhibits effector T cell activation, regulatory T cell expansion and survival,… read more here.
Keywords: dac; treatment; therapeutic efficacy; role innate ... See more keywords