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   Articles with "role kras" as a keyword



The Role of KRAS Status Among Patients Undergoing Staged Versus Simultaneous Resection for Synchronous Colorectal Liver Metastases

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recommendations! Published in 2025 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.70040

Abstract: This study aimed to evaluate the impact of surgical timing—simultaneous versus staged resection—on outcomes of patients with colorectal liver metastases (CRLM) in relation to KRAS mutation status, which is a key factor affecting prognosis. read more here.

Keywords: liver metastases; resection; role kras; colorectal liver ... See more keywords

Abstract A019: The role of KRAS ubiquitination in lung cancer heterogeneity

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recommendations! Published in 2023 at "Molecular Cancer Research"

DOI: 10.1158/1557-3125.ras23-a019

Abstract: Lung cancer is the most frequent cancer with an aggressive clinical course and high mortality rates. About 30% of non-small lung cancer is driven by activating mutations in KRAS (Kirsten rat sarcoma virus). KRAS signaling… read more here.

Keywords: role kras; lung cancer; lztr1; kras ubiquitination ... See more keywords

An emerging role of KRAS in biogenesis, cargo sorting and uptake of cancer-derived extracellular vesicles.

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recommendations! Published in 2022 at "Future medicinal chemistry"

DOI: 10.4155/fmc-2021-0332

Abstract: Extracellular vesicles (EVs) are nanovesicles secreted for intercellular communication with endosomal network regulating secretion of small EVs (or exosomes) that play roles in cancer progression. As an essential oncoprotein, Kirsten rat sarcoma virus (KRAS) is… read more here.

Keywords: role kras; extracellular vesicles; biogenesis cargo; cancer ... See more keywords
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Role of KRAS in NSCLC: present and future

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recommendations! Published in 2018 at "Genetics and Molecular Research"

DOI: 10.4238/gmr16039873

Abstract: Lung cancer is the leading cause of cancer-related deaths worldwide. Despite therapeutic advances over the last several decades, the overall 5-year survival remains only 16%. (Siegel R, 2013). Molecular studies have indicated that Adenocarcinomas have… read more here.

Keywords: kras nsclc; nsclc present; cancer; present future ... See more keywords