Articles with "role lncrnas" as a keyword



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The role of lncRNAs in signaling pathway implicated in CC

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26835

Abstract: Cervical cancer (CC) is the second most common malignancy in females. Owing to poor diagnosis, resistance to the systemic therapies, and high recurrence rate, patients with CC have a relatively poor prognosis. The role of… read more here.

Keywords: signaling pathway; biology; role; pathway implicated ... See more keywords

Emerging role of lncRNAs in the normal and diseased intestinal barrier

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Published in 2018 at "Inflammation Research"

DOI: 10.1007/s00011-018-1170-7

Abstract: ObjectiveA significant effort has been made to understand the intestinal barrier, but the effective means to prevent, reduce, and restore intestinal mucosal damage remains unclear. Recently, a few of studies have explained the mechanism of… read more here.

Keywords: barrier; intestinal barrier; emerging role; lncrnas normal ... See more keywords

The potential role of lncRNAs in osteoporosis

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Published in 2021 at "Journal of Bone and Mineral Metabolism"

DOI: 10.1007/s00774-021-01205-6

Abstract: Osteoporosis is a common bone disease characterized by low bone mass and deterioration of bone microstructure, which predisposes to higher risks of bone fragility and bone fracture. Long non-coding RNAs (lncRNAs) are a class of… read more here.

Keywords: function; bone; lncrnas osteoporosis; potential role ... See more keywords

Role of lncRNAs in the Development of Ischemic Stroke and Their Therapeutic Potential.

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Published in 2021 at "Molecular neurobiology"

DOI: 10.1007/s12035-021-02359-0

Abstract: Stroke is a major cause of premature mortality and disability around the world. Therefore, identification of cellular and molecular processes implicated in the pathogenesis and progression of ischemic stroke has become a priority. Long non-coding… read more here.

Keywords: role lncrnas; ischemic stroke; development; stroke ... See more keywords

Differential sex-dependent role of lncRNAs in cardiomyopathy

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Published in 2024 at "Cardiovascular Research"

DOI: 10.1093/cvr/cvae088.013

Abstract: Funding Acknowledgements  Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Ministry of Education and Science Cardiovascular diseases are one of the most prevalent causes of mortality and morbidity worldwide. Structural… read more here.

Keywords: role; lncrnas cardiomyopathy; sex dependent; expression ... See more keywords

The potential role of lncRNAs in diabetes and diabetic microvascular complications.

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Published in 2020 at "Endocrine journal"

DOI: 10.1507/endocrj.ej19-0574

Abstract: Long noncoding RNAs (lncRNAs) are a group of noncoding RNAs that are longer than 200 nucleotides without protein-coding potential. Becasuse of which these RNAs have no significant protein-coding potential, they were initially considered as "junk-products"… read more here.

Keywords: potential role; role lncrnas; diabetes diabetic; diabetic microvascular ... See more keywords

The role of lncRNAs and XIST in oral cancer

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.826650

Abstract: Long non-coding RNA (lncRNA) plays a significant role in the pathogenesis of many human malignant tumors, including oral cancer. LncRNA can act as a gene regulator in a variety of cancers. It regulates the growth… read more here.

Keywords: role lncrnas; role; oral cancer; lncrnas xist ... See more keywords
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Role of LncRNAs and CircRNAs in Bone Metabolism and Osteoporosis

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Published in 2020 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2020.584118

Abstract: Bone is a mechanosensitive organ that provides strength and support. Many bone cells, various pathways, and signaling molecules coordinate bone metabolism and also determine the course of bone diseases, such as osteoporosis, osteonecrosis, osteopenia, etc.… read more here.

Keywords: circrnas bone; bone; bone metabolism; role lncrnas ... See more keywords

Emerging role of lncRNAs in osteoarthritis: An updated review

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.982773

Abstract: Osteoarthritis (OA) is a prevalent joint disease, which is associated with progressive articular cartilage loss, synovial inflammation, subchondral sclerosis and meniscus injury. The molecular mechanism underlying OA pathogenesis is multifactorial. Long non-coding RNAs (lncRNAs) are… read more here.

Keywords: role lncrnas; osteoarthritis updated; lncrnas osteoarthritis; updated review ... See more keywords

The Role of lncRNAs in the Pathobiology and Clinical Behavior of Multiple Myeloma

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Published in 2021 at "Cancers"

DOI: 10.3390/cancers13081976

Abstract: Simple Summary Multiple myeloma (MM), the second most common hematological neoplasm, is still considered an incurable disease. Long non-coding RNAs (lncRNAs), genes that do not encode proteins, participate in numerous biological processes, but their deregulation,… read more here.

Keywords: lncrnas pathobiology; multiple myeloma; non coding; role ... See more keywords

The Role of lncRNAs in Complicated Pregnancy: A Systematic Review

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Published in 2025 at "Genes"

DOI: 10.3390/genes16080959

Abstract: Background/Objectives: Long non-coding RNAs (lncRNAs) play a crucial role in trophoblast invasion, immune tolerance, and placental angiogenesis. To delineate their diagnostic and pathological significance, we critically evaluated the evidence for correlations between circulating or placental… read more here.

Keywords: lncrnas complicated; pregnancy systematic; role; complicated pregnancy ... See more keywords