Zebrafish mutants reveal unexpected role of Lrp5 in osteoclast regulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.985304
Abstract: Low-density Lipoprotein Receptor-related Protein 5 (LRP5) functions as a co-receptor for Wnt ligands, controlling expression of genes involved in osteogenesis. In humans, loss-of-function mutations in LRP5 cause Osteoporosis-Pseudoglioma syndrome, a low bone mass disorder, while… read more here.
Keywords: function; zebrafish mutants; bone; role lrp5 ... See more keywords