Role of Lysosomal Gene Variants in Modulating GBA ‐Associated Parkinson's Disease Risk
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DOI: 10.1002/mds.28987
Abstract: To date, variants in the GBA gene represent the most frequent large‐effect genetic factor associated with Parkinson's disease (PD). However, the reason why individuals with the same GBA variant may or may not develop neurodegeneration… read more here.
Keywords: associated parkinson; lysosomal gene; parkinson disease; role lysosomal ... See more keywords
The Key Role of Lysosomal Protease Cathepsins in Viral Infections
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DOI: 10.3390/ijms23169089
Abstract: Cathepsins encompass a family of lysosomal proteases that mediate protein degradation and turnover. Although mainly localized in the endolysosomal compartment, cathepsins are also found in the cytoplasm, nucleus, and extracellular space, where they are involved… read more here.
Keywords: cathepsins viral; viral infections; protease cathepsins; role lysosomal ... See more keywords