A role for m6A RNA methylation in heart failure development?
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1714
Abstract: Heart failure persists as a significant cause of death and low quality of life. It is a major public health issue of which the prevalence continues to rise. In industrialized countries, heart failure affects near… read more here.
Keywords: heart; heart failure; m6a rna; development ... See more keywords
The role of m6A mRNA modification in normal and malignant hematopoiesis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiad061
Abstract: Hematopoiesis is a highly orchestrated biological process sustaining the supply of leukocytes involved in the maintenance of immunity, O2 and CO2 exchange, and wound healing throughout the life-time of an animal including human. During early… read more here.
Keywords: modification; malignant hematopoiesis; role m6a; mrna modification ... See more keywords
The Prognostic Role of m6A-Related Genes in Paediatric Neuroblastoma Patients
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/8354932
Abstract: Methods The gene expression data were extracted from the “Therapeutically Applicable Research to Generate Effective Treatments” (TARGET) database. The differentially expressed genes (DEGs) were identified, and the relationships between DEGs and m6A genes were explored.… read more here.
Keywords: role m6a; igf2bp3 mettl14; prognostic role; m6a genes ... See more keywords
Emerging role of m6A methylation modification in ovarian cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Cell International"
DOI: 10.1186/s12935-021-02371-3
Abstract: m6A (N6-methyladenosine) methylation, a well-known modification in tumour epigenetics, dynamically and reversibly fine tunes the entire process of RNA metabolism. Aberrant levels of m6A and its regulators, which can predict the survival and outcomes of… read more here.
Keywords: cancer; methylation; modification; role m6a ... See more keywords
Insights into the Regulatory Role of m6A Epitranscriptome in Glioblastoma
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21082816
Abstract: N6-methyladenosine (m6A) is one of the most widespread and abundant internal messenger RNA modifications found in eukaryotes. Emerging evidence suggests that this modification is strongly linked to the activation and inhibition of cancer pathways and… read more here.
Keywords: regulatory role; glioblastoma; insights regulatory; m6a ... See more keywords