The role of macrophage in regulating tumour microenvironment and the strategies for reprogramming tumour-associated macrophages in antitumour therapy.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2021.151153
Abstract: Tumour-associated macrophages (TAMs) that present abundantly in the tumour microenvironment (TME) exhibit a protumour property, such as promoting genetic instability, tumour metastasis and immunosuppression. Macrophage-targeted therapeutic approaches hence have been applied and shown their significances… read more here.
Keywords: tumour associated; macrophage; role macrophage; associated macrophages ... See more keywords
Insights into the Role of Macrophage Polarization in the Pathogenesis of Osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2485959
Abstract: Millions of people worldwide suffer from osteoporosis, which causes bone fragility and increases the risk of fractures. Osteoporosis is closely related to the inhibition of osteogenesis and the enhancement of osteoclastogenesis. In addition, chronic inflammation… read more here.
Keywords: macrophage polarization; role macrophage; insights role; osteoporosis ... See more keywords
The role of macrophage-derived TGF-β1 on SiO2-induced pulmonary fibrosis: A review
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology and Industrial Health"
DOI: 10.1177/0748233721989896
Abstract: Silicosis is an occupational fibrotic lung disease caused by inhaling large amounts of crystalline silica dust. Transforming growth factor-β1 (TGF-β1), which is secreted from macrophages, has an important role in the development of this disease.… read more here.
Keywords: role macrophage; review; pulmonary fibrosis; silicosis ... See more keywords
The role of macrophage subsets in and around the heart in modulating cardiac homeostasis and pathophysiology
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1111819
Abstract: Cardiac and pericardial macrophages contribute to both homeostatic and pathophysiological processes. Recent advances have identified a vast repertoire of these macrophage populations in and around the heart - broadly categorized into a CCR2+/CCR2- dichotomy. While… read more here.
Keywords: role macrophage; macrophage; cardiac pericardial; around heart ... See more keywords