Decoding the Role of MDM2 as a Potential Ubiquitin E3 Ligase and Identifying the Therapeutic Efficiency of Alkaloids against MDM2 in Combating Glioblastoma
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c07904
Abstract: Glioblastomas (GBMs) represent the most aggressive form of brain tumor arising from the malignant transformation of astrocytes. Despite various advancements, treatment options remain limited to chemotherapy and radiotherapy followed by surgery giving an overall survival… read more here.
Keywords: glioblastoma; mdm2; role mdm2; ligase ... See more keywords
Role of Mdm2 Cascade in Human Cancers
Sign Up to like & getrecommendations! Published in 2017 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2017.00396.1
Abstract: Mdm2 is a well known oncogene which affects expression of various genetic factors. It encoded oncoprotein Mdm2 of 491 amino acids divided into four major domains (p53-binding, acidic, Zn-finger and ring finger). Acting as an… read more here.
Keywords: human cancers; role mdm2; mdm2; cascade human ... See more keywords