Role of microRNAs in doxorubicin-induced cardiotoxicity: an overview of preclinical models and cancer patients
Sign Up to like & getrecommendations! Published in 2017 at "Heart Failure Reviews"
DOI: 10.1007/s10741-017-9653-0
Abstract: Cardiotoxicity is a well-known side effect of doxorubicin (DOX), but the mechanisms leading to this phenomenon are still not completely clear. Prediction of drug-induced dysfunction onset is difficult and is still largely based on detection… read more here.
Keywords: dox induced; induced cardiotoxicity; micrornas doxorubicin; cardiotoxicity ... See more keywords
The role of microRNAs in diseases and related signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06725-y
Abstract: MicroRNAs (miRNAs) are epigenetic regulators of the gene expression and act through posttranslational modification. They bind to 3'-UTR of target mRNAs to inhibit translation or increase the degradation mRNA in many tissues. Any alteration in… read more here.
Keywords: signaling pathways; diseases related; related signaling; role ... See more keywords
The role of microRNAs in brain metastasis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-023-04541-x
Abstract: Brain metastasis (BM) is the most common type of brain tumor and frequently foreshadows disease progression and poor overall survival with patients having a median survival of 6 months. 70,000 new cases of BM are… read more here.
Keywords: role micrornas; brain metastasis; brain; micrornas brain ... See more keywords
Exploring the role of microRNAs as diagnostic and prognostic biomarkers in canine mammary tumors
Sign Up to like & getrecommendations! Published in 2024 at "GeroScience"
DOI: 10.1007/s11357-024-01260-7
Abstract: Canine mammary tumors (CMTs) represent a significant health concern in dogs, with a high incidence among intact female dogs. CMTs are a promising comparative model for human breast cancer, due to sharing several pathophysiological features.… read more here.
Keywords: role micrornas; exploring role; micrornas diagnostic; mammary tumors ... See more keywords
Role of microRNAs As Biomarkers in Sepsis-Associated Encephalopathy
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Neurobiology"
DOI: 10.1007/s12035-021-02445-3
Abstract: Sepsis-associated encephalopathy (SAE) is a neurological complication of sepsis, characterized by brain dysfunction without any direct central nervous system infection. The diagnosis of SAE is currently a challenge. In fact, problems in making a diagnosis… read more here.
Keywords: micrornas biomarkers; diagnosis; associated encephalopathy; sepsis associated ... See more keywords
The role of microRNAs in bone development.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115760
Abstract: Epigenetic regulation is critical for proper bone development. Evidence from a large body of published literature informs us that microRNAs (miRNAs) are important epigenetic factors that control many aspects of bone development, homeostasis, and repair… read more here.
Keywords: mirna; bone; bone development; section ... See more keywords
Role of microRNAs in programmed cell death in renal diseases: A review
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033453
Abstract: MicroRNAs (miRNAs) regulate gene expression involving kidney morphogenesis and cell proliferation, apoptosis, differentiation, migration, invasion, immune evasion, and extracellular matrix remodeling. Programmed cell death (PCD) is mediated and regulated by specific genes and a wealth… read more here.
Keywords: cell death; cell; role micrornas; renal diseases ... See more keywords
The Role of MicroRNAs in Regulatory T Cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunology Research"
DOI: 10.1155/2020/3232061
Abstract: MicroRNAs are a class of conserved, 20 nt-23 nt long, noncoding small RNAs that inhibit expression of their respective target genes in different cell types. Regulatory T cells (Tregs) are a subpopulation of T cells that negatively… read more here.
Keywords: micrornas regulatory; regulatory cells; role; immunology ... See more keywords
The Role of MicroRNAs in Hyperlipidemia: From Pathogenesis to Therapeutical Application
Sign Up to like & getrecommendations! Published in 2022 at "Mediators of Inflammation"
DOI: 10.1155/2022/3101900
Abstract: Hyperlipidemia is a common metabolic disorder with high morbidity and mortality, which brings heavy burden on social. Understanding its pathogenesis and finding its potential therapeutic targets are the focus of current research in this field.… read more here.
Keywords: application; role micrornas; hyperlipidemia pathogenesis; hyperlipidemia ... See more keywords
Role of MicroRNAs in Cardiac Disease with Stroke in Pregnancy
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/5260085
Abstract: Pregnancy-related cardiovascular disease with stroke remains a considerable source of higher maternal morbidity and mortality occurs in periods of pregnancy, delivery, and postpartum. It is essential to counsel the mother before pregnancy by an expert… read more here.
Keywords: postpartum; cardiac disease; disease; role micrornas ... See more keywords
Abstract 4118: The role of microRNAs in the tumor immune microenvironment
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4118
Abstract: Background: miRNA have been shown to be central communicators between the immune system and cancer. They are attractive as candidate blood-based cancer detection targets because they are secreted in high copy number from cancer cells,… read more here.
Keywords: time; immune checkpoint; role micrornas; tumor immune ... See more keywords