The potential role of miR-124-3p in tumorigenesis and other related diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06347-4
Abstract: MicroRNAs (miRNAs) are a class of single-stranded noncoding and endogenous RNA molecules with a length of 18-25 nucleotides. Previous work has shown that miR-124-3p leads to malignant progression of cancer including cell apoptosis, migration, invasion,… read more here.
Keywords: tumorigenesis; potential role; role mir; cancer ... See more keywords
The expression and role of miR-181a in multiple myeloma
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000012081
Abstract: Abstract This study aims to investigate the role of miR-181a in multiple myeloma (MM). Fresh peripheral blood and bone marrows were collected. Expression of miR-181a, BCL-2 mRNA, and NOVA1 mRNA was detected by RT-qPCR. The… read more here.
Keywords: role mir; multiple myeloma; bone; expression ... See more keywords
Role of miR‐223‐3p in pulmonary arterial hypertension via targeting ITGB3 in the ECM pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cell Proliferation"
DOI: 10.1111/cpr.12550
Abstract: To investigate the functions of miR‐223‐3p and ITGB3 in pulmonary arterial hypertension (PAH). read more here.
Keywords: arterial hypertension; role mir; pulmonary arterial; mir 223 ... See more keywords
The Role of miR-23b in Cancer and Autoimmune Disease
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Oncology"
DOI: 10.1155/2021/6473038
Abstract: Short-stranded miRNAs are single-stranded RNA molecules involved in the regulation of gene expression. miRNAs are involved in a variety of cellular physiological processes, including cell proliferation, differentiation, and apoptosis. miR-23b have been identified to act… read more here.
Keywords: autoimmune; role mir; mir 23b; cancer autoimmune ... See more keywords
A Novel Role for MiR-520a-3p in Regulating EGFR Expression in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000479397
Abstract: Background/Aims: MicroRNAs (miRNAs) have been consistently demonstrated to be involved in colorectal cancer as either tumour oncogenes or tumour suppressors. However, the detailed role of miR-520a-3p in colorectal cancer remains poorly understood. Methods: Quantitative RT-PCR… read more here.
Keywords: role mir; mir 520a; colorectal cancer; egfr expression ... See more keywords
The role of miR-210, E2F3 and ephrin A3 in angiosarcoma cell proliferation
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2017.3084
Abstract: BackgroundAlthough angiosarcoma exhibits aggressive progression and is associated with unfavourable prognosis, its pathogenesis is poorly understood.ObjectivesIn the present study, we investigated the possibility that microRNAs play a role in the pathogenesis of angiosarcoma.Materials & methodsmicroRNA… read more here.
Keywords: e2f3 ephrin; role mir; 210 e2f3; mir 210 ... See more keywords
The role of miR-145 in promoting the fibrosis of pulmonary fibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/19-27-a
Abstract: The effects of miR-145 (microRNA 145) on M. pneumoniae (MP)-infected MRC-5 (Medical Research Council cell strain 5) cell TGF-β/Smad (transforming growth factor beta/Smad) fibrosis pathway were explored through constructing MP-infected MRC-5 cell models. In addition,… read more here.
Keywords: mir 145; tgf smad; role mir; fibrosis ... See more keywords
MicroRNA-1274a serves as a prognostic biomarker in patients with osteosarcoma and is involved in tumor progression via targeting ADAM9.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/20-695-a
Abstract: Osteosarcoma (OS) is the most frequent primary malignancy in bone, and commonly occurs in children and adolescents. The aim of this study was to assess the aberrant expression of miR-1274a in OS patients, and to… read more here.
Keywords: mir 1274a; prognostic biomarker; role mir; progression ... See more keywords
Role of miR-214-5p in the migration and invasion of pancreatic cancer cells.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201811_16255
Abstract: OBJECTIVE To analyze the role of miR-214-5p in proliferation and metastasis of pancreatic cancer (PC) cells, as well as its underlying mechanism. PATIENTS AND METHODS 30 pairs of PC tissues and adjacent normal tissues were… read more here.
Keywords: invasion; role mir; pancreatic cancer; migration ... See more keywords
Role of miR-16-5p in the proliferation and metastasis of hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201901_16757
Abstract: OBJECTIVE The aim of this study was to investigate the role of miR-16-5p in hepatocellular carcinoma (HCC), and to explore the possible underlying mechanism. PATIENTS AND METHODS 100 pairs of cancerous and para-cancerous tissues surgically… read more here.
Keywords: hcc; role mir; mir; proliferation ... See more keywords
Role of miR-182 in cardiovascular and cerebrovascular diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1181515
Abstract: The treatment of cardiovascular and cerebrovascular diseases have undergone major advances in recent decades, allowing for a more effective prevention of cardiovascular and cerebrovascular events. However, cardiac and cerebral atherothrombotic complications still account for substantial… read more here.
Keywords: role mir; mir 182; cerebrovascular diseases; cardiovascular cerebrovascular ... See more keywords