Potential role of mTORC1 and the PI3K-Akt pathway in anti-acne properties of licorice flavonoids
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.103968
Abstract: Abstract We applied a label-free proteomic method to explore the mechanisms of Licorice flavonoid anti-acne effects in rat. Acne model was established in the back of rats as model group (MDL), then treated with licorice… read more here.
Keywords: potential role; role mtorc1; anti acne; pi3k akt ... See more keywords
The central role of mTORC1 in amino acid sensing.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-4403
Abstract: The mechanistic target of rapamycin (mTOR) is a master regulator of cell growth that controls cell homeostasis in response to nutrients, growth factors, and other environmental cues. Recent studies have emphasized the importance of lysosomes… read more here.
Keywords: acid sensing; role mtorc1; mtorc1; central role ... See more keywords
Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20622
Abstract: Hepatoblastoma (HB) is the most common type of liver malignancy in children. Recent studies suggest that activation of Yes-associated protein (YAP) is a major molecular event in HB development, as activated YAP synergizes with mutant… read more here.
Keywords: yap taz; development; yap; role mtorc1 ... See more keywords