The role of NFAT in the pathogenesis and targeted therapy of hematological malignancies.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174889
Abstract: The nuclear factor of activated T cells (NFAT) family is well known for the survival of hemopoietic cells and plays an important role in the immune response. In recent decades, NFAT alteration was discovered in… read more here.
Keywords: role nfat; nfat pathogenesis; pathogenesis targeted; targeted therapy ... See more keywords
Abstract 1936: The central role of NFAT signalling in the mechanism of action of the TRPV6 oncochannel inhibitor and clinical candidate SOR-C13
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-1936
Abstract: SOR-C13, a 13-mer peptide derived from soricidin, the paralytic peptide in saliva of the Northern Short-tailed shrew, has completed an open-label, all comers Phase I Clinical Trial for the treatment of epithelially-derived cancers. SOR-C13 is… read more here.
Keywords: sor c13; role nfat; cancer; trpv6 ... See more keywords