Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2016_56
Abstract: Orexins (hypocretins) are critically involved in coordinating appropriate physiological and behavioral responses to aversive and threatening stimuli. Acute stressors engage orexin neurons via direct projections from stress-sensitive brain regions. Orexin neurons, in turn, facilitate adaptive… read more here.
Keywords: orexin; system; stress; role orexin ... See more keywords
The Insomnia-Addiction Positive Feedback Loop: Role of the Orexin System
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers of neurology and neuroscience"
DOI: 10.1159/000514965
Abstract: Significant sleep impairments often accompany substance use disorders (SUDs). Sleep disturbances in SUD patients are associated with poor clinical outcomes and treatment adherence, emphasizing the importance of normalizing sleep when treating SUDs. Orexins (hypocretins) are… read more here.
Keywords: addiction; orexin; role orexin; orexin system ... See more keywords