The Role of p53 in Determining Mitochondrial Adaptations to Endurance Training in Skeletal Muscle
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32887-0
Abstract: Abstractp53 plays an important role in regulating mitochondrial homeostasis. However, it is unknown whether p53 is required for the physiological and mitochondrial adaptations with exercise training. Furthermore, it is also unknown whether impairments in the… read more here.
Keywords: skeletal muscle; role p53; muscle; mitochondrial adaptations ... See more keywords
The role of p53‐MDM2 signaling in missed abortion and possible pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.15385
Abstract: Missed abortion is one of the common obstetrical and gynecological complications, angiogenesis is the most important factor in fetal and placental development. However, the definite etiology and pathogenesis are not fully understood. read more here.
Keywords: abortion; mdm2 signaling; role p53; p53 mdm2 ... See more keywords
The role of p53 in cancer drug resistance and targeted chemotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13475
Abstract: Cancer has long been a grievous disease complicated by innumerable players aggravating its cure. Many clinical studies demonstrated the prognostic relevance of the tumor suppressor protein p53 for many human tumor types. Overexpression of mutated… read more here.
Keywords: role p53; p53 cancer; cancer; p53 ... See more keywords
The role of p53 in liver fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1057829
Abstract: The tumor suppressor p53 is the central hub of a molecular network, which controls cell proliferation and death, and also plays an important role in the occurrence and development of liver fibrosis. The abundant post-translational… read more here.
Keywords: role p53; liver fibrosis; p53; p53 liver ... See more keywords
The Role of p53-Mediated Signaling in the Therapeutic Response of Colorectal Cancer to 9F, a Spermine-Modified Naphthalene Diimide Derivative
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DOI: 10.3390/cancers12030528
Abstract: Colorectal cancer (CRC) is one of the most prevalent cancers due to its frequency and high rate of mortality. Polyamine-vectorized anticancer drugs possess multiple biological properties. Of these drugs, 9F has been shown to inhibit… read more here.
Keywords: signaling therapeutic; role p53; p53 mediated; colorectal cancer ... See more keywords