Articles with "role pak4" as a keyword



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Abstract 4755: Role of PAK4 in cancer immune cell exclusion

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Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-4755

Abstract: Lack of T-cell infiltration is the main mechanism of primary resistance to checkpoint blockade therapies. Here, we performed a transcriptomic analysis of metastatic melanoma biopsies taken from patients treated with anti-PD1 (n=23) with biopsies pre-… read more here.

Keywords: cancer immune; immune cell; pak4 cancer; role pak4 ... See more keywords