Role of Peroxiredoxins in Protecting Against Cardiovascular and Related Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Toxicology"
DOI: 10.1007/s12012-020-09588-0
Abstract: Peroxiredoxin (Prx) refers to a family of thiol-dependent peroxidases that decompose hydrogen peroxide, lipid hydroperoxides, as well as peroxynitrite, and protect against oxidative and inflammatory stress. There are six mammalian Prx isozymes (Prx1–6), classified as… read more here.
Keywords: peroxiredoxins protecting; cardiovascular related; role peroxiredoxins; protecting cardiovascular ... See more keywords
A role for peroxiredoxins in H2O2- and MEKK-dependent activation of the p38 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Redox Biology"
DOI: 10.1016/j.redox.2019.101340
Abstract: The p38 mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in the cellular response to various stresses and its deregulation accompanies pathological conditions such as cancer and chronic inflammation. Hydrogen peroxide (H2O2) is… read more here.
Keywords: role peroxiredoxins; p38; signaling pathway; activation ... See more keywords
The Role of Peroxiredoxins in the Regulation of Sepsis
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DOI: 10.3390/antiox11010126
Abstract: Oxidative stress, a result of a disturbance in redox homeostasis, is considered to be one of the main aggravating events in the pathogenesis of immune disorders. Peroxiredoxins (Prdxs) are an enzyme family that catalyzes the… read more here.
Keywords: sepsis; prdxs; peroxiredoxins regulation; role peroxiredoxins ... See more keywords
The Role of Peroxiredoxins in Cancer Development
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12050666
Abstract: Simple Summary Reactive oxygen species (ROS) are unstable derivatives of oxygen that are generated naturally as products or biproducts of biological reactions. ROS, such as hydrogen peroxide, can be utilized for defense against infectious agents… read more here.
Keywords: cancer development; peroxiredoxins cancer; role peroxiredoxins; prxs ... See more keywords