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Published in 2020 at "Cellular Signalling"
DOI: 10.1016/j.cellsig.2020.109761
Abstract: A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the execution of the inflammatory response. The zymogen/proenzyme plasminogen is converted to the serine protease plasmin, a key fibrinolytic factor by plasminogen…
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Keywords:
plasminogen;
role plasminogen;
inflammation;
inflammatory response ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22052304
Abstract: Fibrinolytic factors like plasminogen, tissue-type plasminogen activator (tPA), and urokinase plasminogen activator (uPA) dissolve clots. Though mere extracellular-matrix-degrading enzymes, fibrinolytic factors interfere with many processes during primary cancer growth and metastasis. Their many receptors give…
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Keywords:
plasminogen;
role plasminogen;
cancer;
multifaceted role ... See more keywords