The role of polyamines in the regulation of macrophage polarization and function
Sign Up to like & getrecommendations! Published in 2019 at "Amino Acids"
DOI: 10.1007/s00726-019-02719-0
Abstract: Naturally occurring polyamines are ubiquitously distributed and play important roles in cell development, amino acid and protein synthesis, oxidative DNA damage, proliferation, and cellular differentiation. Macrophages are essential in the innate immune response, and contribute… read more here.
Keywords: polyamines regulation; macrophage polarization; role polyamines; regulation macrophage ... See more keywords
The role of polyamines in gastric cancer
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DOI: 10.1038/s41388-021-01862-x
Abstract: Advancements in our understanding of polyamine molecular and cellular functions have led to increased interest in targeting polyamine metabolism for anticancer therapeutic benefits. The polyamines putrescine, spermidine, and spermine are polycationic alkylamines commonly found in… read more here.
Keywords: gastric cancer; polyamine; role polyamines; polyamines gastric ... See more keywords
Role of Polyamines in Parasite Cell Architecture and Function.
Sign Up to like & getrecommendations! Published in 2017 at "Current pharmaceutical design"
DOI: 10.2174/1381612823666170703163458
Abstract: In the absence of accessible, effective vaccines, the fight against parasitic disease relies mostly on chemotherapy. Nevertheless, the considerable side effects, high costs and growing number of refractory cases comprise substantial drawbacks. Thus, the search… read more here.
Keywords: microscopy; cell architecture; role polyamines; polyamines parasite ... See more keywords
Role of Polyamines as Biomarkers in Lymphoma Patients: A Pilot Study
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DOI: 10.3390/diagnostics12092151
Abstract: Lymphomas represent a heterogeneous and widely diversified group of neoplastic diseases rising from a variety of lymphoid subsets at heterogeneous differentiation stages. These lymphoproliferative disorders lead to the clinicopathological complexity of the classification of lymphoid… read more here.
Keywords: role; polyamines biomarkers; biomarkers lymphoma; patients pilot ... See more keywords
Role of Polyamines and Hypusine in β Cells and Diabetes Pathogenesis
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DOI: 10.3390/metabo12040344
Abstract: The polyamines—putrescine, spermidine, and spermine—are polycationic, low molecular weight amines with cellular functions primarily related to mRNA translation and cell proliferation. Polyamines partly exert their effects via the hypusine pathway, wherein the polyamine spermidine provides… read more here.
Keywords: role polyamines; cells diabetes; translation; hypusine cells ... See more keywords